CPAP与口腔矫治器治疗阻塞型睡眠呼吸暂停综合症的疗效比较

发布时间：2018-04-21 22:45

本文选题：CPAP + 口腔矫治器　；参考：《山西医科大学》2011年硕士论文

【摘要】：目的：本研究前瞻性比较CPAP和口腔矫治器对阻塞型睡眠呼吸暂停综合症患者的治疗效果，观察分析患者治疗前后主观感受、PSG（多导睡眠图）疗效变化、患者治疗过程中舒适度及治疗选择倾向，从而探讨其临床疗效，为临床提供指导。方法：选择2008.10-2010.10期间就诊于山西医科大学第一医院呼吸科的中重度OSAS患者30例，将患者随机分组，分别采用口腔矫治器和CPAP治疗，分析比较患者治疗6个月后PSG疗效及主观症状变化。按照Bonham等提出的有关OSAS的疗效评定标准评价治疗效果。实验数据采用SPSS17.0统计学软件进行分析。结果：CPAP与口腔矫治器治疗组前后PSG疗效比较发现：CPAP与口腔矫治器治疗组前各指标比较差异无统计学意义；组内治疗前后各指标比较，差异有统计学意义；CPAP与口腔矫治器组治疗后比较差异无统计学意义。CPAP与口腔矫治器治疗组治疗前后主观疗效比较：除记忆力减退、晨起头痛、头晕、反应迟钝这4项外，P0.05，差异有统计学意义。CPAP治疗组治疗前后比较：除记忆力减退、反应迟钝这2项外，P0.05，差异有统计学意义；口腔矫治器与CPAP治疗组治疗后各指标比较，差异无统计学意义。口腔矫治器治疗组与CPAP治疗组戴用后舒适度比较,差异有统计学意义。结论：（1）两种治疗方法均可用于中重度OSAS的治疗，且疗效可靠；CPAP与口腔矫治器两种治疗方法疗效相近，可以互为替代疗法。（2）主观疗效比较CPAP比口腔矫治器更适合治疗中重度OSAS患者。（3）口腔矫治器由于其见效快、轻巧、舒适、携带方便、价格低，多数患者更倾向使用。
[Abstract]:Objective: to compare the efficacy of CPAP and oral appliance in the treatment of obstructive sleep apnea syndrome (OSAS), and to observe and analyze the changes of subjective perception of PSG (polysomnography) before and after treatment. In order to explore the clinical effect and provide guidance for clinical treatment, the patients' comfort and treatment choice tendency were discussed in the course of treatment. Methods: thirty patients with moderate and severe OSAS who were admitted to the Department of Respiratory, the first Hospital of Shanxi Medical University from October to October, 2008.were randomly divided into two groups. The patients were treated with oral appliance and CPAP respectively. Objective: to analyze and compare the effect of PSG and the change of subjective symptoms after 6 months of treatment. The efficacy of OSAS was evaluated according to the criteria proposed by Bonham et al. The experimental data were analyzed by SPSS17.0 software. Results there was no significant difference in PSG between the two groups before and after treatment, but there was no significant difference between the two groups before and after treatment. There was no significant difference between CPAP and oral appliance group after treatment. CPAP and oral appliance treatment group before and after treatment of subjective efficacy comparison: except memory loss, morning headache, dizziness, There were significant differences in the four items (P0.05, P 0.05) between the two groups: except memory loss and slowness, there were significant differences between the two groups, and the indexes of oral appliance and CPAP treatment group were compared after treatment. The difference was not statistically significant. There was significant difference between the oral appliance treatment group and the CPAP treatment group after wearing comfort. Conclusion the two methods can be used in the treatment of moderate and severe OSAS, and the curative effect is similar to that of oral appliance. Compared with oral appliance, CPAP is more suitable for treatment of moderate and severe OSAS patients because of its quick effect, light, comfortable, easy to carry and low price. Most patients prefer to use it.
【学位授予单位】：山西医科大学
【学位级别】：硕士
【学位授予年份】：2011
【分类号】：R766

【参考文献】