Pentacam与SL-OCT测量对原发性闭角型青光眼患者激光周边虹膜切开手术前后中央前房深度的相关性分析

发布时间：2018-04-26 15:02

本文选题：Pentacam + 裂隙灯光学相干断层成像术　；参考：《第三军医大学学报》2014年12期

【摘要】：目的评估Pentacam与SL-OCT测量原发性闭角型青光眼(primary angle-closure glaucoma,PACG)应用激光周边虹膜切开术(laser peripheral iridoplasty,LPI)手术前后中央前房深度(center anterior chamber depth,CACD)的差异性、相关性和一致性。方法在我院眼科门诊筛查PACG患者中符合行LPI术的病例共58例(58眼),应用眼前节分析系统Pentacam和裂隙灯光学相干断层成像术(slit-lamp-adapted optical coherence tomography,SL-OCT)分别对PACG患者进行CACD测量,分别记录LPI术前,术后1 d、1周、1个月参数。结果 Pentacam测得PACG患者LPI术前,术后1 d、1周及1个月的CACD分别为(1.60±0.31)、(1.65±0.28)、(1.62±0.30)、(1.61±0.31)mm。SL-OCT测量LPI术前,术后1 d、1周及1个月的CACD分别为(1.70±0.30)、(1.73±0.30)、(1.71±0.31)、(1.72±0.31)mm。2种测量方式LPI术前与术后各时间比较,差异均无统计学意义(P0.05);而2种测量方式之间相比较,术前及术后相同时间点差异均具有统计学意义(P0.01)。Pentacam与SL-OCT测量PACG患者LPI术前,术后1 d、1周及1个月的CACD值均存在显著相关关系(r=0.929,P0.001;r=0.962,P0.001;r=0.961,P0.001;r=0.951,P0.001)。通过Bland-Altman分析方法,Pentacam与SL-OCT测量LPI术前,术后1 d、1周及1个月CACD差异的95%置信界限分别为-0.33~0.12、-0.29~0.08、-0.25~0.08、-0.26~0.07 mm。结论 Pentacam与SL-OCT测量PACG患者LPI术后CACD具有高度一致性和相关性,二者均可作为青光眼临床筛查的辅助检查方式,为患者提供了有效的无创且可量化的便捷检查。
[Abstract]:Objective to evaluate the difference, correlation and consistency of central anterior chamber depth anterior chamber before and after laser peripheral irido iridoplasty with Pentacam and SL-OCT measurements of primary angle-closure glaucoma (angle-closure glaucoma). Methods 58 cases (58 eyes) of PACG patients who were in accordance with LPI in our hospital were examined by Pentacam and slit lamp optical coherence tomography (slit-lamp-adapted optical coherence tomographySL-OCTT). The CACD of PACG patients was recorded before LPI. The parameters were 1 week and 1 month after operation. Results the CACD of LPI in PACG patients was 1.60 卤0.31 and 1.65 卤0.28 卤1.61 卤0.31)mm.SL-OCT before 1 day and 1 month after PACG, respectively. The CACD of 1 week and 1 month after operation were 1.70 卤0.301.73 卤0.30 卤1.71 卤0.31 卤1.72 卤0.31)mm.2, respectively, compared with each time before and after LPI, the CACD of 1 week and 1 month after operation were 1.70 卤0.301.73 卤0.30 卤1.71 卤0.31 卤1.72 卤1.72 卤0.31)mm.2, respectively, and the CACD of 1 week and 1 month after operation were 1.70 卤0.301.73 卤0.30 卤1.71 卤1.72 卤1.72 卤0.31)mm.2, respectively. There was no significant difference between the two measurement methods (P 0.05), but there were significant differences between the two methods before and after operation (P 0.01). Pentacam was significantly correlated with the value of CACD before LPI 1 week and 1 month after SL-OCT in patients with PACG. There was a significant correlation between the CACD values of 0. 929 P 0. 001 P 0. 962% P 0. 001 ~ 0. 961g P 0. 001 P 0. 001 P 0. 001 P 0. 001 P 0. 001 P 0. 001 P 0. 001 P 0. 001 P 0. 001 P 0. 001 P 0. 001 P 0. 001 P 0. 001 P 0. 001 P 0. 001 P 0. 001 P 0. 001 and 1 month after the operation. The 95% confidence limit of CACD difference at 1 week and 1 month after LPI was measured by Bland-Altman and SL-OCT. The 95% confidence limit of CACD difference was -0.33 ~ 0.12 ~ (-0.29) ~ 0.08 ~ (-0.25) ~ 0.08 ~ 0.26 ~ 0.07 mm 路min ~ (-1), respectively. Conclusion Pentacam and SL-OCT have high consistency and correlation in the measurement of CACD after LPI in PACG patients. Both of them can be used as auxiliary examination for clinical screening of glaucoma and provide effective noninvasive and quantifiable convenient examination for patients.
【作者单位】：第三军医大学大坪医院野战外科研究所眼科;
【分类号】：R779.63

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