球后注射曲安奈德治疗后巩膜炎的临床观察

发布时间：2018-04-28 23:35

  本文选题：后巩膜炎 + 曲安奈德　； 参考：《吉林大学》2011年硕士论文

【摘要】：目的： 评价球后注射曲安奈德(TA)治疗后巩膜炎的临床疗效。 方法： 回顾性分析2007年1月-2010年12月间诊治的后巩膜炎患者17例17眼,患者均经球后注射曲安奈德20mg,每两周一次,连续治疗2-3个月,随访观察治疗前后的视力、眼底、眼压、眼B超检查和部分患者的荧光素眼底血管造影(FFA)、光学相干断层扫描(OCT)检查。随访3个月-1年。 结果： 到最后一次随访时,所有患者经治疗后眼红、眼周疼痛等症状消失。视力提高12眼(70.6%),视力不变5眼(29.4%)。治疗前及最后一次随访时,平均视力为0.32、0.79(P0.05)。B超检查后巩膜厚度(4.354±1.55)mm、(1.25+0.45)mm(P0.05),后巩膜及筋膜水肿消失,“T”形征消失。FFA示治疗后视网膜的荧光素渗漏明显减轻。OCT示视网膜神经上皮层复位,视网膜水肿消失,脉络膜皱褶消失。所有患者随访期间眼压均≤21mmHg。2例患者治疗后3-6个月后巩膜炎复发。 结论： 1、球后注射曲安奈德可有效治疗后巩膜炎。2、球后注射曲安奈德治疗后巩膜炎操作简便、安全性高,无严重糖皮质激素全身副作用和局部注射并发症发生。
[Abstract]:Objective: To evaluate the clinical effect of retrobulbar injection of triamcinolone acetonide (TAA) in the treatment of posterior scleral inflammation. Methods: From January 2007 to December 2010, 17 patients (17 eyes) with posterior scleral inflammation were treated with triamcinolone acetonide 20mg by retrobulbar injection. The visual acuity, fundus and intraocular pressure were observed after 2 to 3 months of continuous treatment. Ophthalmic ultrasonography and fluorescein fundus angiography (FFAA) and optical coherence tomography (Oct) were performed in some patients. The patients were followed up for 3 months to 1 year. Results: By the last follow-up, all patients were treated with eye redness and eye pain. Visual acuity was improved in 12 eyes (70.6%) and unchanged in 5 eyes (29.4%). Before treatment and at the last follow-up, the average visual acuity was 0.32 卤0.79 P0.05. Scleral thickness was 4.354 卤1.55mm / 1.25 0.45mm / P0.05, edema of posterior sclera and fascia disappeared, and "T" sign disappeared. FFA showed that the leakage of fluorescein in retina decreased significantly after treatment. Oct showed that retinal nerve epithelium was reattached. Retinal edema disappeared and choroidal folds disappeared. All patients with intraocular pressure 鈮，

本文编号：1817428