清窦灵合剂鼻腔冲洗治疗慢性鼻-鼻窦炎鼻内镜术后临床研究

发布时间：2018-04-30 21:34

本文选题：鼻腔冲洗 + 清窦灵合剂　；参考：《南京中医药大学学报》2014年05期

【摘要】：目的观察清窦灵合剂鼻腔冲洗对慢性鼻-鼻窦炎鼻内镜术后患者的临床疗效。方法 60例慢性鼻-鼻窦炎鼻内镜术后患者随机分为治疗组和对照组各30例,对照组采用0.9%的氯化钠注射液鼻腔冲洗,治疗组采用0.9%的氯化钠注射液中加入清窦灵合剂鼻腔冲洗,测定2组术前及术后1个月、3个月、6个月鼻黏膜纤毛传输速率(MTR);随访6个月以上,观察2组临床疗效。结果术后1个月及术后3个月治疗组MTR比对照组增快,2组差异有显著性意义(P0.05);术后6个月2组MTR差异无显著性意义(P0.05);术后3个月、6个月2组疗效比较,治疗组病情完全控制率、总有效率均明显高于对照组,差异有显著性意义(P0.05)。结论清窦灵合剂鼻腔冲洗在控制鼻腔炎症、减少分泌物,改善患者的临床症状,减轻术腔水肿,防止肉芽及囊泡形成,促进术腔上皮化,促进鼻黏膜纤毛功能早期恢复等方面均有较好疗效。
[Abstract]:Objective to observe the clinical effect of nasal irrigation with Qingdouling mixture on patients with chronic rhinosinusitis after endoscopic surgery. Methods 60 patients with chronic rhinosinusitis after endoscopic sinus surgery were randomly divided into treatment group (n = 30) and control group (n = 30). The control group was treated with 0.9% sodium chloride injection. In the treatment group, the nasal cavity irrigation of Qingdouling mixture was added to 0.9% sodium chloride injection, and the nasal mucosal ciliary transmission rate was measured before and 1 month, 3 months and 6 months after operation in the two groups, and the clinical effect of the two groups was observed after 6 months follow-up. Results there was a significant difference in MTR between the two groups at 1 month and 3 months after operation compared with the control group (P 0.05), but there was no significant difference in MTR between the two groups at 6 months after operation (P 0.05), and after 3 months and 6 months after operation, the complete control rate of the disease in the treatment group was compared with that in the two groups. The total effective rate was significantly higher than that of the control group (P 0.05). Conclusion nasal cavity irrigation with Qingdouling mixture can control nasal inflammation, reduce secretion, improve clinical symptoms, relieve edema, prevent granulation and vesicle formation, and promote epithelization of operative cavity. To promote the early recovery of nasal mucosal cilium function and other aspects have a good effect.
【作者单位】：湖北民族学院附属民大医院;恩施州中心医院支助中心;
【基金】：湖北省教育厅科研基金资助项目(B20101908)
【分类号】：R765.9

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