不同致敏变应原所致变应性鼻炎患者164例生活质量调查

发布时间：2018-05-04 02:46

本文选题：鼻炎 + 变应性　；参考：《临床耳鼻咽喉头颈外科杂志》2015年03期

【摘要】：目的:比较中国北方地区树木花粉、杂草花粉以及尘螨引起的变应性鼻炎(AR)患者的生活质量水平,伴随哮喘情况,探讨AR患者的生活质量与变应原血清特异性IgE的关系。方法:选取164例AR伴或不伴哮喘的成人患者,完成病史采集及变应原检查,并填写标准化鼻结膜炎生存质量调查问卷(RQLQ)。结果:中国北方地区AR患者中,树木花粉组及杂草花粉组的RQLQ总评分、日常活动评分、鼻部症状及眼部症状评分均显著高于尘螨组,生活质量更差。树木花粉组的哮喘比例明显低于尘螨组,而杂草花粉组的哮喘比例则与尘螨组无明显差异,且显著高于树木花粉组。尘螨及蒿属花粉过敏所致的AR患者的RQLQ评分与其变应原特异性IgE水平之间无明显相关性。结论:AR患者的生活质量评分受到变应原具体类型的影响,中国北方地区花粉过敏者发病时的生活质量比尘螨过敏者更差,但生活质量受损程度可能不受变应原特异性IgE水平的影响。不同花粉过敏所致鼻炎合并哮喘的比例不同,杂草花粉可能比树木花粉更容易诱发哮喘。
[Abstract]:Objective: to compare the quality of life (QOL) of the patients with allergic rhinitis caused by dust mite and tree pollen, weed pollen and dust mite induced allergic rhinitis in northern China, and to explore the relationship between the quality of life of AR patients and allergen serum-specific IgE. Methods: 164 adult patients with or without AR were selected to complete the history collection and allergen examination and fill out the standardized rhinoconjunctivitis quality of life questionnaire (RQLQQ). Results: the RQLQ score, daily activity score, nasal symptom and eye symptom score of tree pollen group and weed pollen group were significantly higher than those of dust mite group, and the quality of life was worse. The asthma rate of tree pollen group was significantly lower than that of dust mite group, while the asthma rate of weed pollen group was not significantly different from that of dust mite group, and was significantly higher than that of tree pollen group. There was no significant correlation between RQLQ score and allergen-specific IgE level in AR patients caused by dust mite and artemisia pollen allergy. Conclusion the quality of life score of patients with 10% AR is affected by the specific types of allergens. The quality of life of pollen allergies in northern China is worse than that of dust mite allergies. However, the degree of impairment of quality of life may not be affected by the level of allergen-specific IgE. The incidence of rhinitis associated with asthma varies with pollen allergy. Weed pollen may induce asthma more easily than tree pollen.
【作者单位】：中国医学科学院北京协和医院变态反应科;
【分类号】：R765.21

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