准分子激光前弹力层下角膜磨镶术与准分子激光原位角膜磨镶术术后干眼的临床对比研究

发布时间：2018-05-08 03:12

本文选题：准分子激光前弹力层下角膜磨镶术 + 准分子激光原位角膜磨镶术　；参考：《眼科新进展》2014年02期

【摘要】：目的探讨准分子激光前弹力层下角膜磨镶术(sub-Browman’s keratomileusis,SBK)与准分子激光原位角膜磨镶术(laser in situ keratomileusis,LASIK)术后不同时间干眼的症状及相关指标的变化。方法回顾性分析2010年3月至2011年12月在我院接受准分子激光手术的近视患者。行SBK者106例(212眼)为SBK组,行LASIK者130例(260眼)为LASIK组,分别观察术前及术后1周、1个月、3个月、6个月干眼症状、角膜荧光素染色、非侵入性泪膜破裂时间、基础泪液分泌量,并进行统计学分析。结果术后1个月和3个月SBK组分别有47眼(22.2%)和25眼(11.8%)出现干眼症状,而LASIK组分别有139眼(53.5%)和92眼(35.4%),两组比较差异均有统计学意义(均为P0.05)。术后1个月和3个月SBK组分别有39眼(18.4%)和18眼(8.5%)出现角膜着色,而LASIK组分别为125眼(48.1%)和81眼(31.2%),两组比较差异均有统计学意义(均为P0.05)。术后1个月、3个月SBK组基础泪液分泌量和非侵入性泪膜破裂时间分别为(11.28±1.51)mm、(11.56±1.32)s和(13.57±2.36)mm、(14.39±1.01)s,LASIK组分别为(7.45±1.29)mm、(7.83±2.15)s和(8.15±1.80)mm、(8.57±1.46)s,两组比较差异均有统计学意义(均为P0.05)。至术后6个月,以上各项指标两组比较差异均无统计学意义(均为P0.05)。结论 SBK较LASIK治疗近视术后干眼发生率低,恢复快。
[Abstract]:Objective to investigate the changes in the symptoms and related indexes of dry eyes at different time after excimer laser pre elastic layer sub-Browman s keratomileusis (SBK) and excimer laser in situ keratomileusis (laser in situ keratomileusis, LASIK). Methods a retrospective analysis was carried out in our hospital from March 2010 to December 2011. 106 cases (212 eyes) of SBK in group SBK and 130 cases (260 eyes) of LASIK were treated as group LASIK. The symptoms of dry eyes were observed before and 1 weeks, 1 months, 3 months, 6 months, corneal fluorescein staining, non invasive tear film time, the secretion of the base tear, and statistical analysis. The results were 1 months and 3 months after the operation, and the results were statistically analyzed. There were 47 eyes (22.2%) and 25 eyes (11.8%) with dry eye symptoms in group LASIK, 139 eyes (53.5%) and 92 eyes (35.4%) respectively. The difference in the two group was statistically significant (P0.05). There were 39 eyes (18.4%) and 25 eyes in the group of SBK after 1 months and 3 months respectively. The differences were statistically significant (all P0.05). 1 months after operation, 3 months and 3 months, the tear secretion and noninvasive tear film rupture time were (11.28 + 1.51) mm, (11.56 + 1.32) s and (13.57 + 2.36) mm, (14.39 + 1.01) s, LASIK group (7.45 + 1.29) mm, (7.83 + 11.28) mm, and S. There were statistical significance (all P0.05). To 6 months after operation, there was no statistical difference between the two groups (all P0.05). Conclusion SBK was lower in the incidence of dry eye after myopia and faster recovery than LASIK.

【作者单位】：河北医科大学第一医院眼科;
【分类号】：R779.63

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