阻塞性睡眠呼吸暂停低通气综合征患者血清网膜素水平的研究

发布时间：2018-05-08 02:04

本文选题：阻塞性睡眠呼吸暂停低通气综合征 + 网膜素　；参考：《中国卫生检验杂志》2014年14期

【摘要】：目的探讨阻塞性睡眠呼吸暂停低通气综合征(Obstructive sleep apnea hypopnea syndrome,OSAHS)患者血清网膜素(Omentin)水平的变化及意义。方法选取80名经睡眠多导图监测的受试者,根据体质量指数和呼吸暂停低通气指数将其分为3组,对照组、超重非OSAHS组、超重OSAHS组,其中超重OSAHS组中有12名受试者进行了一晚经鼻持续气道正压通气(nasal continuous positive airway pressure,nCPAP)治疗。测定3组受试者以及12名经一晚nCPAP治疗患者的血清Omentin、空腹血糖、血脂。结果超重OSAHS组患者血清Omentin水平较超重非OSAHS组明显降低(P0.05)。结论超重OSAHS组患者中Omentin水平下降,提示Omentin可能参与了OSAHS的发生。
[Abstract]:Objective to investigate the changes and significance of serum omentin (Omentin) level in patients with obstructive sleep apnea hypopnea syndrome (Obstructive sleep apnea hypopnea syndrome, OSAHS). Methods 80 subjects monitored by sleep polygraph were selected and divided into 3 groups according to the body mass index and the exhalation hypoventilation index, and the control group was overweight. In the non OSAHS group, the overweight OSAHS group, of which 12 subjects in the overweight OSAHS group were treated with nasal continuous positive airway pressure (nasal continuous positive airway pressure, nCPAP) for one night. The serum Omentin, fasting blood glucose, and blood lipid were measured in 3 groups of subjects and 12 patients treated with one night nCPAP. The level of N was significantly lower than that in overweight non OSAHS group (P0.05). Conclusion the level of Omentin in overweight OSAHS group decreased, suggesting that Omentin might be involved in the occurrence of OSAHS.

【作者单位】：河北北方学院;中国医学科学院北京协和医院;
【分类号】：R766

【共引文献】