幼年型复发性呼吸道乳头状瘤临床影响因素分析

发布时间：2018-05-08 09:19

  本文选题：乳头状瘤 + 乳头状瘤病毒　； 参考：《临床耳鼻咽喉头颈外科杂志》2014年23期

【摘要】：目的:探讨影响幼年型复发性呼吸道乳头状瘤临床病程和严重程度的因素。方法:回顾分析幼年型复发性呼吸道乳头状瘤患儿的临床资料,分别按发病年龄、首次复发年龄、首次复发间期、性别、有无气管切开进行分组,并对病变严重程度评分与受累的亚区、手术间期以及再次手术的间期进行相关性分析。结果:按复发年龄分为≤4岁组和4岁组,2组在手术次数和平均、最短、最长手术间期差异有统计学意义(P值分别为0.029,0.003,0.010,0.039),而按发病年龄分组(≤4岁组和4岁组)则差异无统计学意义(P值分别为0.154,0.219,0.194,0.219);病灶严重程度评分与受累的亚区呈正相关(r=0.914,P=0.000),与复发间期呈负相关(r=-0.451,P=0.000);发病年龄≤4岁组和4岁组在病灶严重程度和手术间期上差异均有统计学意义(P值分别为0.036,0.000),而按手术年龄分组则无明显差异(P值分别为0.103,0.813);行气管切开术的患儿接受更多的手术,但在发病年龄、复发年龄及复发间期等上未见明显差异。结论:准确评估幼年型复发性呼吸道乳头状瘤临床病程的发展趋势,首先要考虑首次复发年龄及间期,判断病灶严重程度需考虑发病年龄及病变受累的亚区。
[Abstract]:Objective: to investigate the factors influencing the clinical course and severity of juvenile recurrent respiratory papilloma. Methods: the clinical data of children with juvenile recurrent respiratory papilloma were retrospectively analyzed. According to age of onset, age of first recurrence, first recurrence interval, sex, tracheotomy or not, The correlation between the severity score and the affected subarea, the interval of operation and the interval of reoperation was analyzed. Results: according to the recurrence age, the patients were divided into two groups: 鈮，

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