急性中心性浆液性脉络膜视网膜病变FFA与频域OCT图像对比研究

发布时间：2018-05-16 14:01

本文选题：中心性浆液性脉络膜视网膜病变 + 渗漏点　；参考：《眼科新进展》2015年08期

【摘要】：目的观察急性中心性浆液性脉络膜视网膜病变(central serous chorioretinopathy,CSC)荧光素眼底血管造影(fundus fluorescein angiography,FFA)和频域光学相干断层扫描(frequency domain optical coherence tomography,FD-OCT)图像特征,对比研究2种检查方法定位病灶的一致性。方法回顾性分析79例急性CSC患者(81眼)的FFA和FD-OCT图像资料,观察患眼FFA荧光素渗漏点与FD-OCT中视网膜色素上皮(retinal pigment epithelium,RPE)异常改变的对应关系。结果 81眼急性CSC患眼中,FFA检查发现荧光素渗漏点86个,在FD-OCT图像上表现为视网膜色素上皮脱离(pigment epithelial detachment,PED)、小隆起、粗糙紊乱等RPE层异常改变。此外尚有13眼(16.05%)在荧光素渗漏点以外区域存在着低荧光、荧光染色、透见荧光,在FDOCT上RPE亦表现为PED、小隆起、粗糙紊乱混合存在。还有6眼(7.41%)无任何异常荧光区域,在FD-OCT上RPE也显示有PED、小隆起、粗糙紊乱等改变。结论急性CSC的FFA渗漏点与FD-OCT中RPE异常改变部位基本对应,而FFA渗漏点以外区域FD-OCT亦有RPE层异常改变,在急性CSC诊治中FD-OCT不可完全替代FFA。
[Abstract]:Objective to observe the features of fundus fluorescein angiography (FFA) and frequency-domain optical coherence tomography (FD-OCTs) images of central serous chorioretinopathy (serous) in acute central serous chorioretinopathy, and to compare the consistency between the two methods. Methods the FFA and FD-OCT images of 79 patients with acute CSC (81 eyes) were retrospectively analyzed, and the relationship between the FFA fluorescein leakage point and the abnormal changes of retinal pigment epithelium (RPE) in FD-OCT was observed. Results 86 fluorescein leakage points were found in 81 eyes with acute CSC. On FD-OCT images, abnormal changes of RPE layer such as retinal pigment epithelium detachment epithelial detachment, small protuberance and rough disorder were found. In addition, 13 eyes (16.05 eyes) had low fluorescence, fluorescent staining and transparent fluorescence outside the leakage point of fluorescein, and RPE on FDOCT also appeared as ped, small protuberance, rough mixed existence. There were no abnormal fluorescence areas in 6 eyes (7.41). RPE also showed PED, small bulge and rough disorder on FD-OCT. Conclusion the site of FFA leakage in acute CSC is basically corresponding to the site of RPE abnormal change in FD-OCT, and there is also abnormal change of RPE layer in FD-OCT outside FFA leakage point. FD-OCT is not a complete substitute for RPE in the diagnosis and treatment of acute CSC.
【作者单位】：南昌大学第一附属医院眼科;
【基金】：国家自然科学基金资助(编号:81160118;81460092;81400372) 全国临床医药研究专项基金(编号:L2012052) 江西省远航工程(编号:2014022) 江西省学位与研究生教育教学改革研究项目(编号:2015) 江西省科技平台建设项目(编号:2013116) 江西省青年科学基金(编号:20151BAB215016) 江西省科技支撑计划项目(编号:20151BBG70223) 江西省教育厅科技计划项目(编号:GJJ14170) 江西省卫计委科技计划项目(编号:20155154)~~
【分类号】：R774.1

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