LASIK治疗近视散光眼术后高阶像差变化的多因素分析

发布时间：2018-05-21 21:33

本文选题：准分子激光原位角膜磨镶术 + 高阶像差　；参考：《眼科新进展》2014年04期

【摘要】：目的探讨LASIK治疗近视散光眼术后高阶像差变化与切削量、治疗光区直径和术后角膜后表面前凸值的相关性。方法随机选取采用飞秒激光制瓣波前像差引导LASIK治疗的近视散光患者69例(138眼),采集患者术前和术后6个月的高阶像差值、角膜后表面前凸值,记录患者的治疗光区直径和切削量,采用多元逐级回归分析探讨手术切削量、治疗光区直径和术后角膜后表面前凸值与术后高阶像差的相关性。结果术中手术切削量为(96.26±25.14)μm,治疗光区直径为(6324.00±297.00)μm,术后6个月角膜后表面前凸值为(47.62±15.00)μm;术后6个月瞳孔直径6 mm区的总体高阶像差和去球差高阶像差均方根值分别为(0.78±0.26)μm、(0.56±0.23)μm,术前为(0.49±0.21)μm、(0.45±0.22)μm,差异均有统计学意义(均为P0.01)。术后6个月瞳孔直径6 mm区的总体高阶像差和去球差高阶像差均方根值与手术切削量(r=0.62、0.46,均为P0.01)、术后角膜后表面前凸值(r=0.49、0.45,均为P0.01)均呈正线性相关,与治疗光区直径(r=-0.56、-0.47,均为P0.01)均呈负线性相关。结论 LASIK治疗近视散光眼术后高阶像差较术前增大,术后高阶像差增加与手术切削量、术后角膜后表面前凸值呈正线性相关,与治疗光区直径呈负线性相关。
[Abstract]:Objective to investigate the correlation between the changes of higher-order aberrations and the amount of ablation, the diameter of the treated light area and the postoperative corneal surface kyphosis after LASIK for myopic astigmatism. Methods 69 patients with myopic astigmatism treated by femtosecond laser wavefront aberration guided LASIK were randomly selected. The diameter of the treated light area and the amount of ablation were recorded. The correlation between the diameter of the treated light area and the postoperative corneal surface protruding value and the postoperative high order aberration was investigated by multiple stepwise regression analysis. Results the mean value of total high order aberration and high order aberration in 6 months after operation were 0.78 卤0.26 渭 m and 0.56 卤0.23 渭 m, respectively, and the mean square value of total high order aberration and despherical aberration were 0.78 卤0.26 渭 m, 6324.00 卤297.00 渭 m and 47.62 卤15.00 渭 m, respectively, 6 months after operation, and the mean square value of high order aberration in 6 mm area of pupil diameter was 0.78 卤0.26 渭 m, 0.56 卤0.23 渭 m, respectively, in 6 months after operation, the mean square value of high order aberration in 6 mm area of pupil diameter was 0.78 卤0.26 渭 m. The former was 0.49 卤0.21) 渭 m (0.45 卤0.22) 渭 m, the difference was statistically significant (P 0.01). The root mean square values of high order aberration and high order aberration in 6 mm area of pupil diameter 6 months after operation were positively correlated with the mean square value of high order aberration and the mean square value of high order aberration in the area of pupil diameter 6 months after operation (P 0. 01, P 0. 01). The mean square values of total high order aberration and high order aberration in 6 mm area of pupillary diameter were all positively correlated with the mean square value of the total high order aberration and the high order aberration in the area of 6 mm pupil diameter. There was a negative linear correlation between the treatment and the diameter of the light area, ru-0. 56g-0. 47 (P 0. 01). Conclusion the higher order aberration after LASIK for myopic astigmatism is larger than that before operation. The increase of high order aberration after operation is positively linear with the amount of operation and corneal surface kyphosis after operation, and it is negatively correlated with the diameter of the treated light area.
【作者单位】：山东中医药大学附属眼科医院;
【分类号】：R779.63

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