变应性因素及变应性鼻炎与慢性鼻-鼻窦炎鼻息肉的相关性探讨

发布时间：2018-06-03 13:30

本文选题：鼻炎 + 变应性　；参考：《临床耳鼻咽喉头颈外科杂志》2014年17期

【摘要】：目的:探讨变应性因素及变应性鼻炎(AR)与慢性鼻-鼻窦炎鼻息肉的临床相关性。方法:将200例研究对象分为A、B组,A组诊断为AR(110例),B组诊断为慢性鼻-鼻窦炎鼻息肉(90例),通过欧蒙印迹法定量检测血清sIgE浓度并观察慢性鼻-鼻窦炎鼻息肉手术治疗后的复发率、AR并发慢性鼻-鼻窦炎鼻息肉的发生率。结果:A组sIgE总阳性率为89.09%,B组sIgE总阳性率为74.44%。B组中sIgE阳性者术后复发率为58.21%,sIgE阴性者术后复发率为8.70%。A组41例(37.27%)并发慢性鼻-鼻窦炎鼻息肉,血清sIgE阳性率为97.56%;69例(62.73%)未并发慢性鼻-鼻窦炎鼻息肉,血清sIgE阳性率为79.71%;组内slgE阳性率比较差异有统计学意义(χ2=6.96,P0.01)。结论:变应性因素及AR与慢性鼻-鼻窦炎鼻息肉的发生有一定的相关性,提示避免接触变应原、合理治疗AR能够有效控制慢性鼻-鼻窦炎鼻息肉的复发率。
[Abstract]:Objective: to investigate the relationship between allergic factors and allergic rhinitis and nasal polyps of chronic rhinosinusitis. Methods: two hundred patients were divided into two groups: group A (AR(110) and group B (90 cases of chronic rhinosinusitis and nasal polyposis). Serum sIgE levels were measured by Ormon blotting method and the operation of chronic rhinosinusitis and nasal polyps was observed. Recurrence rate after treatment: AR associated with chronic rhinosinusitis and nasal polyps. Results the total positive rate of sIgE in group A was 89.09. The total positive rate of sIgE in group B was 74.44. The recurrence rate of sIgE positive group was 58.21. The recurrence rate of group A was 8.70%. In group A, 41 cases of rhinosinusitis and nasal polyps were complicated with chronic rhinosinusitis and nasal polyps. The positive rate of serum sIgE was 97.56% and the positive rate of serum sIgE was 79.71% in 69 cases with chronic rhinosinusitis and nasal polyps (蠂 26.96% P 0.01). Conclusion: allergic factors and AR are related to the occurrence of chronic rhinosinusitis and nasal polyps, which suggests that avoiding contact with allergens and reasonably treating AR can effectively control the recurrence rate of chronic rhinosinusitis and nasal polyps.
【作者单位】：济南军区总医院耳鼻咽喉头颈外科;
【分类号】：R765.21

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