实验性钩突切除对于上颌窦气体力学的影响

发布时间：2018-06-07 13:11

本文选题：鼻腔 + 鼻窦炎　；参考：《吉林大学》2010年硕士论文

【摘要】： 鼻腔结构的任何细微变化都会导致通过鼻腔的气流发生一系列相应的变化如气体流量、压强等数据的改变,这有可能导致诸如慢性鼻-鼻窦炎等鼻科疾病,对鼻腔气流流场的深入研究有利于进一步认识鼻腔结构与功能之间的关系。目前而言自奥地利学者Messerklinger开创了鼻内窥镜鼻窦外科手术的新领域以来,鼻窦外科取得了革命性进步,并逐步发展成为功能性内窥镜鼻窦外科。长期以来有许多学者对鼻窦炎进行了大量的研究证实了诸如感染因素、变态反应因素、纤毛引流等其他因素的影响,但手术后由于鼻腔内部结构改变而引发鼻腔气流力学的变化仍却一直缺乏足够的认识。这是因为长期以来,对于鼻腔气体动力学的研究一直处于初级阶段。上世纪八十年代,人们主要通过制作各种材质的等比例或放大比例的鼻腔尸源性实体模型,并向模型中注入各种形式的含有示踪成分的流体来观察鼻腔气流场。进入九十年代后则是应用影像学数据构建模型,并以此为基础应用高性能计算机和现代大型流体分析商业软件进一步研究人体生理状态下鼻腔内流流场变化。但是受制于早期模型制备工艺的粗糙以及CT、MRI等检查设备的分辨率限制和信号损失,以上这些方法不能准确的反应鼻腔气流场的真实情况,故本文旨在于利用人体尸头标本结合高灵敏度的微型电子测量元件反映出鼻腔气流场的真实情况。并希望可以通过该研究进一步改进手术方式,临床治疗的效果。
[Abstract]:Any slight change in the structure of the nasal cavity will result in a series of corresponding changes in the airflow through the nasal cavity, such as changes in gas flow, pressure, etc., which may lead to nasal diseases such as chronic rhinosinusitis. The further study on the flow field of nasal cavity is helpful to further understand the relationship between the structure and function of nasal cavity. At present, since Austrian scholar Messerklinger initiated a new field of endoscopic sinus surgery, sinus surgery has made revolutionary progress, and gradually developed into functional endoscopic sinus surgery. For a long time, many scholars have done a lot of research on sinusitis to confirm the influence of other factors, such as infection factors, allergy factors, cilia drainage and so on. However, the change of airflow mechanics of nasal cavity caused by the change of nasal cavity structure after operation is still lack of enough understanding. This is because the study of nasal aerodynamics has been in its infancy for a long time. In the eighties of the last century, the nasal cavity airflow field was observed mainly by making the nasal cavity cadaveric solid model with equal proportion or magnification ratio of various materials, and injecting various kinds of fluid with tracer components into the model. In the 1990s, the imaging data were used to build the model, and based on it, the changes of the flow field in the nasal cavity under the physiological state of the human body were further studied by using the high performance computer and the modern large-scale fluid analysis commercial software. However, these methods can not accurately reflect the true situation of the nasal airflow field because of the roughness of the early model preparation process and the resolution limitation and signal loss of the equipment such as CTT / MRI. Therefore, the purpose of this paper is to reflect the real situation of the nasal airflow field by using the human cadaveric head specimen and the high sensitivity micro electronic measuring element. We also hope that we can further improve the operation and clinical treatment through this study.
【学位授予单位】：吉林大学
【学位级别】：硕士
【学位授予年份】：2010
【分类号】：R765.9

【参考文献】