鼻咽癌患者血浆中S100A8和S100A9蛋白浓度测定及临床意义

发布时间：2018-06-23 10:52

  本文选题：鼻咽癌 + SA蛋白　； 参考：《临床检验杂志》2014年04期

【摘要】：目的探讨鼻咽癌患者血浆中S100A8和S100A9蛋白水平与临床分期及血浆EB病毒VCA-IgA抗体的相关性。方法用ELISA法检测鼻咽癌患者(Ⅱ期36例,Ⅲ期104例,Ⅳ期104例)和104例体检健康者血浆中S100A8、S100A9蛋白浓度和EB病毒VCA-IgA抗体水平,用SPSS 16.0统计软件进行数据分析。结果鼻咽癌患者血浆中S100A8、S100A9蛋白浓度分别为0.44(0.25,0.78)ng/mL和202.71(185.79,238.54)pg/mL,显著高于体检健康者0.29(0.18,0.44)ng/mL和192.43(170.66,193.42)pg/mL(P均0.05)。Ⅱ、Ⅲ、Ⅳ期鼻咽癌患者血浆S100A8、S100A9蛋白浓度均高于体检健康者(P均0.05),且Ⅱ、Ⅲ期鼻咽癌患者血浆中S100A8、S100A9蛋白浓度高于Ⅳ期(P0.05);Ⅲ期S100A9蛋白浓度高于Ⅱ期(P0.05)。相关分析结果显示,鼻咽癌患者血浆中S100A8、S100A9蛋白浓度与EB病毒VCA-IgA抗体水平无相关性(r分别为-0.04,-0.07,P均0.05)。结论鼻咽癌患者血浆中S100A8和S100A9蛋白水平升高,且与临床分期有关。
[Abstract]:Objective to investigate the correlation between plasma S100A8 and S100A9 protein levels and clinical stage and EB virus VCA-IgA antibody in patients with nasopharyngeal carcinoma (NPC). Methods the concentration of S100A8 S100A9 protein and the level of EB virus VCA-IgA antibody in plasma of patients with nasopharyngeal carcinoma (36 cases in stage 鈪，

本文编号：2056880