突发性聋挽救性治疗时机

发布时间：2018-06-25 03:28

本文选题：听觉丧失 + 突发性　；参考：《临床耳鼻咽喉头颈外科杂志》2015年08期

【摘要】：目的:探讨突发性聋挽救性治疗的最佳时机,以最大限度地提高突发性聋的疗效。方法:192例突发性聋患者纳入研究,其中63例一直接受全身激素治疗的初始治疗方案;其余患者在不同时间点开始鼓室激素注射的挽救性治疗:从初始治疗第3天后开始者29例,第7天后开始者38例,第14天后开始者43例,第1个月后开始者19例。所有患者随访2个月。结果:初始治疗第3天、第7天及第1个月判断为无效的患者,接受鼓室激素注射与未接受鼓室激素注射比较,其治愈率及总有效率差异均无统计学意义。初始治疗第14天接受与未接受鼓室激素注射者,治愈率和总有效率差异均有统计学意义(P0.05)。结论:1在突发性聋治疗中,鼓室激素注射治疗作为初始治疗方案与全身激素治疗方案疗效相当;2鼓室激素注射治疗更适于作为全身激素治疗失败后的挽救性治疗;3鼓室激素注射治疗作为挽救性治疗的最佳时机是在接受全身激素治疗后的第2周左右。
[Abstract]:Objective: to explore the best time of rescue therapy for sudden deafness and to improve the curative effect of sudden deafness. Methods Twenty two patients with sudden deafness were included in the study, 63 of them received the initial therapy of systemic hormone therapy, and the remaining patients began the rescue therapy of tympanic hormone injection at different time points: 29 patients started from the third day after the initial treatment. 38 cases began after 7 days, 43 cases started after 14 days, and 19 cases started after the first month. All patients were followed up for 2 months. Results: there was no significant difference in the cure rate and the total effective rate between the patients who were treated with tympanic hormone injection on the 3rd day, the 7th day and the first month. The cure rate and total effective rate were significantly different between those who received or not received tympanic hormone injection on the 14th day of initial treatment (P0.05). Conclusion in the treatment of sudden deafness, The therapeutic effect of tympanic hormone injection is equivalent to that of systemic hormone injection therapy. It is more suitable for rescue therapy after systemic hormone therapy failure. The best time for rescue therapy is about 2 weeks after systemic hormone therapy.
【作者单位】：湖南师范大学医学院第二附属医院(解放军第163中心医院)耳鼻咽喉科;
【分类号】：R764.437

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