声反射咽腔测量对阻塞性睡眠呼吸暂停低通气综合征患者咽腔结构和功能的研究

发布时间：2018-06-27 23:31

本文选题：声学 + 咽　；参考：《临床耳鼻咽喉头颈外科杂志》2014年12期

【摘要】：目的:采用一种新的声反射咽腔测量方法评估健康成人、单纯打鼾及阻塞性睡眠呼吸暂停低通气综合征(OSAHS)患者的咽腔结构和功能。方法:采用前瞻性研究设计。对85例正常成人,11例单纯打鼾者及45例OSAHS患者进行声反射咽腔测量,并记录各研究参数,包括口咽结合处距离及面积,会厌游离缘距离及面积,声门处距离及面积,4条曲线的变异系数、咽腔长度、咽腔平均横截面积及咽腔容积。结果:对该方法的重复性评价发现,12h内的两次测量结果示咽腔长度(Z=-0.881,P=0.378),咽腔容积(Z=-0.196,P=0.844),咽腔平均横截面积(Z=-0.668,P=0.504)差异无统计学意义。正常组与重度OSAHS组之间口咽结合处的面积(χ2=23.453,P=0.000),会厌游离缘的面积(χ2=6.632,P=0.036),声门处的面积(χ2=20.955,P=0.000),4条曲线的变异系数(χ2=7.047,P=0.029),咽腔平均横截面积(χ2=26.923,P=0.000),咽腔容积(χ2=26.529,P=0.000),均差异有统计学意义。BMI、颈围及疾病严重程度分组与口咽结合处的面积、声门处的面积、咽腔平均横截面积及咽腔容积呈负相关。结论:这种新的声反射咽腔测量方法重复性好,并可为OSAHS的诊断甚至分级诊断提供新的临床思路。
[Abstract]:Objective: to evaluate the structure and function of pharyngeal cavity in healthy adults, patients with simple snoring and obstructive sleep apnea hypopnea syndrome (OSAHS) by a new method of acoustic reflex pharyngeal cavity measurement. Methods: prospective study design was used. The acoustic reflex pharyngeal cavity was measured in 85 normal adults with simple snoring and 45 patients with OSAHS. The parameters of the study were recorded, including the distance and area of the oropharynx junction, the distance and area of the free edge of epiglottis. The variation coefficient of 4 curves of glottis distance and area, the length of pharyngeal cavity, the average cross sectional area of pharyngeal cavity and the volume of pharynx cavity. Results: the reproducibility of the method showed that there was no significant difference in the length of pharynx (Z ~ (-0.881), the volume of pharynx (Z ~ (-0.196) and the average cross-sectional area of pharynx (Z ~ (-0.668) P ~ (0.504) within 12 h. The area of the oropharyngeal junction between the normal group and the severe OSAHS group (蠂 223.453), the area of the free edge of epiglottis (蠂 2) 6.632U / P 0.036, the area of glottis (蠂 ~ 2 + 20.955P ~ (0.000), the coefficient of variation of the four curves (蠂 ~ 27.047 / P ~ (0.029), the average cross-sectional area of pharynx (蠂 ~ 2 = 26.923P ~ (0.000), the volume of pharynx cavity (蠂 ~ (2) 26.529P ~ (0.000), respectively. And the area where the severity of the disease is grouped with oropharynx, The area of glottis, the average cross-sectional area of pharyngeal cavity and the volume of pharyngeal cavity were negatively correlated. Conclusion: this new acoustic reflex pharyngeal cavity measurement method is reproducible and can provide a new clinical idea for the diagnosis and even grading diagnosis of OSAHS.
【作者单位】：广州医科大学附属第二医院耳鼻咽喉科;
【分类号】：R766

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