探讨非线性动力学方法在嗓音声学评估中的应用

发布时间：2018-06-29 15:57

本文选题：离体狗喉 + 发声信号　；参考：《福建医科大学》2013年硕士论文

【摘要】：第一部分采用非线性动力学方法研究声门下压对离体狗喉声音质量的影响目的：探讨声门下压（SGP）变化和离体狗喉声音质量变化之间的关系及非线性动力学分析方法和扰动分析方法在区别发音信号中的应用。方法：收集6只离体狗喉分别在SGP为2kpa和4kpa时的发音信号，采用非线性动力学方法和扰动方法分析，，比较非线性动力学参数相空间重构、关联维D2和扰动方法参数jitter、shimmer、基频（F0）和噪谐比（NHR）对压力变化的敏感性。结果：SGP在4kpa时的相空间重构较SGP在2kpa时的复杂，D2、jitter、shimmer、F0和NHR在SGP在4kpa和2kpa时的差异有统计学意义（P0.05）；60次的声学信号中因不能提取稳定频率有21次无法使用扰动方法进行分析，SGP为4kpa时的发声信号不能分析次数较SGP为2kpa时多，差异有统计学意义（P0.05）。结论：声音质量在SGP为4kpa时较SGP为2kpa更好；离体狗喉发声信号的不规则性与SGP大小有关；非线性动力学方法分析声学信号的应用较扰动方法更具敏感性。第二部分非线性动力学方法在分析声带息肉、囊肿患者嗓音信号中的应用目的：评估和比较传统扰动方法和非线性动力学方法分析正常和声带息肉、囊肿患者的嗓音信号能力。方法：应用扰动方法测量声学微扰参数如基频微扰百分比（jitter percent）、振幅微扰百分比（shimmer percent）和应用非线性方法重构相空间、计算关联维（D2）分析75例受试对象的嗓音信号，比较结果并分析。结果：正常受试者嗓音信号的jitter、shimmer和D2值均低于声带息肉和声带囊肿患者，差异有统计学意义（P0.05）,而jitter、shimmer和D2值在声带息肉和声带囊肿患者之间的差异没有统计学意义（P0.05）,声带息肉和声带囊肿患者嗓音信号的重构相空间复杂程度相似，但比正常人复杂。D2值在ROC曲线（receiver operating characteristic curve）下的面积小于jitter和shimmer值，其中5例患者嗓音信号不能应用扰动方法分析，而非线性动力学方法均可分析。结论：扰动方法和非线性动力学方法分析嗓音信号对声带息肉和声带囊肿患者异常嗓音均有诊断价值。扰动方法在诊断声带息肉和声带囊肿异常嗓音的特异性上优于非线性动力学方法，但对信号的规则性要求较高，适应性较低，非线性动力学方法可作为扰动方法的重要补充。第三部分非线性动力学分析方法在声带息肉手术疗效评估中的应用目的：通过观察声带息肉手术前后嗓音信号的非线性动力学参数和扰动参数，探讨非线性动力学方法分析声带息肉手术前后嗓音信号的应用价值。方法：收集41例嗓音显微微瓣声带息肉患者手术前及术后6周的嗓音信号，分别应用扰动方法测量声学微扰参数如基频微扰百分比（jitter percent）、振幅微扰百分比（shimmer percent）和应用非线性方法重构相空间、计算关联维（D2），比较分析。结果：有4例患者嗓音信号jitter和shimmer值偏大不能应用扰动方法分析而被剔除，患者术后嗓音信号的jitter、shimmer和D2值均低于术前，其中D2值和女性患者的shimmer值术前、术后差异有统计学意义（p0.01），jitter值术前、术后差异无统计学意义（p0.01）。结论：非线性动力学分析方法较扰动方法更能显著评估声带息肉手术前后的治疗效应；对于不规则的嗓音信号，扰动方法的应用有限制，非线性动力学分析方法仍可评估其治疗效应。
[Abstract]:the first portion

Study on the effect of the depression on throat sound quality of isolated dog by nonlinear dynamic method

Objective : To study the relationship between the changes of sound - door depression ( SGP ) and the changes of sound quality of isolated dog ' s throat and the application of nonlinear dynamic analysis method and disturbance analysis method in distinguishing the pronunciation signal .

Methods : The pronunciation signals of 6 isolated dog ' s throat in SGP of 2kpa and 4kpa were collected , and the sensitivity of nonlinear dynamic parameter phase space reconstruction , correlation dimension D2 and disturbance method parameters jitter , shimmer , fundamental frequency ( F0 ) and noise ratio ( NHR ) on pressure change were compared by means of nonlinear dynamic method and perturbation method .

Results : The spatial reconstruction of SGP at 4kpa was more complex than SGP at 2kpa , and D2 , jitter , shimmer , F0 and NHR had statistical significance at 4 kpa and 2kpa ( P0.05 ) .
In 60 acoustic signals , it was not possible to extract stable frequency for 21 times , and the frequency of speech signal could not be analyzed at 4 kpa than that of SGP ( 2 kpa ) , and the difference was statistically significant ( P0.05 ) .

Conclusion : The sound quality is 2kpa better than SGP when SGP is 4kpa ;
The irregularity of the vocal signal of the isolated dog was related to the size of SGP ;
The application of nonlinear dynamic method to analyze acoustic signal is more sensitive than the perturbation method .

the second part

Application of nonlinear dynamic method in analyzing vocal cord polyp and cyst patient ' s voice signal

Objective : To evaluate and compare the traditional perturbation method and nonlinear dynamics method to analyze the voice signal capacity of patients with normal and vocal cord polyps and cysts .

Methods : The interference method was applied to measure the acoustic perturbation parameters , such as jitter percent , shimmer percent , and nonlinear method to reconstruct the phase space . The correlation dimension ( D2 ) was calculated to analyze the voice signals of 75 subjects , and the results were compared and analyzed .

Results : The jitter , shimmer and D2 values of the voice signals in normal subjects were lower than those in vocal cord polyps and vocal cord cysts ( P0.05 ) , but the difference of jitter , shimmer and D2 between vocal cord polyps and vocal cord cysts was not statistically significant ( P0.05 ) . The area under receiver operating characteristic curve was smaller than that of normal subjects .

Conclusion : The method of perturbation and non - linear dynamics are valuable for the diagnosis of abnormal voice of vocal cord polyp and vocal cord cyst . The disturbance method is superior to non - linear dynamic method in the diagnosis of abnormal voice of vocal cord polyp and vocal cord cyst , but the regularity of the signal is high and the adaptability is low , and the nonlinear dynamic method can be used as an important supplement to the disturbance method .

PART III

Application of nonlinear dynamic analysis method in evaluating the efficacy of vocal cord polyp surgery

Objective : To explore the application value of non - linear dynamic method to analyze the voice signal before and after vocal cord polyp operation by observing the nonlinear dynamic parameters and disturbance parameters of the voice signal before and after vocal cord polyp operation .

Methods : The voice signals of 41 patients with vocal cord polyp were collected before and after operation , and the parameters such as jitter percent , shimmer percent and nonlinear method were used to reconstruct the phase space . The correlation dimension ( D2 ) was calculated and the comparative analysis was compared .

Results : There were 4 patients whose voice signal jitter and shimmer value could not be analyzed by the method of perturbation . The jitter , shimmer and D2 values of the voice signals were lower than that before operation .

Conclusion : The nonlinear dynamic analysis method can significantly evaluate the therapeutic effect of vocal cord polyp before and after the operation of vocal cord polyp .
For irregular voice signals , the application of the perturbation method is limited , and the nonlinear dynamic analysis method can evaluate its therapeutic effect .
【学位授予单位】：福建医科大学
【学位级别】：硕士
【学位授予年份】：2013
【分类号】：R767.92

【参考文献】