非肥胖阻塞性睡眠呼吸暂停综合征患者临床特点及危险因素

发布时间：2018-07-03 05:39

  本文选题：阻塞性睡眠呼吸暂停综合征 + 体质量指数　； 参考：《中华高血压杂志》2014年07期

【摘要】：目的了解非肥胖阻塞性睡眠呼吸暂停综合征(OSAS)患者睡眠监测参数、血压、血脂水平及其风险因素。方法连续入选2009年1月至2010年12月新疆维吾尔自治区人民医院睡眠中心及高血压中心就诊的非肥胖高血压患者221例,均行多导联睡眠监测,比较无OSAS组(n=87)和合并OSAS组(n=134)患者睡眠参数、血压及代谢指标,Logistic回归分析OSAS的危险因素。结果合并OSAS组年龄[(51.1±11.1)比(43.9±12.6)岁]、颈围[(36.8±3.1)比(35.5±3.0)cm]、呼吸暂停低通气指数[(14.3比1.3)次/h]、阻塞平均持续时间[(19.9±13.0)比(6.3±8.4)min]、低密度脂蛋白胆固醇(LDL-C)[(2.6±0.8)比(2.3±0.7)mmol/L]明显高于无OSAS组,而白天、夜间及24h平均心率均明显低于无OSAS组(均P0.05)。多因素Logistic回归分析显示,颈围和年龄为非肥胖高血压人群患OSAS的危险因素,其中,颈围≥38cm者患OSAS风险是颈围32cm者的5.97倍(95%CI1.61~22.09),年龄≥65岁者患OSAS风险是年龄35岁者的7.56倍(95%CI1.13~50.52)。结论合并OSAS患者比无OSAS者LDL-C增高,而平均心率减慢。颈围和年龄是非肥胖高血压人群患OSAS的危险因素。
[Abstract]:Objective to investigate sleep monitoring parameters, blood pressure, blood lipids and risk factors in non-obese patients with obstructive sleep apnea syndrome (OSAS). Methods from January 2009 to December 2010, 221 non-obese hypertensive patients were selected from sleep center and hypertension center of Xinjiang Uygur Autonomous region people's Hospital. The sleep parameters, blood pressure and metabolic parameters of patients without OSAS (nong87) and with OSAS (nang134) were compared. Logistic regression analysis was performed on the risk factors of OSAS. Results the age [(51.1 卤11.1) vs (43.9 卤12.6) years], neck circumference [(36.8 卤3.1) vs (35.5 卤3.0) cm], apnea hypopnea index [(14.3 vs 1.3) times / h], mean duration of obstruction [(19.9 卤13.0) vs (6.3 卤8.4) min], low density lipoprotein cholesterol (LDL-C) [(2.6 卤0.8) vs (2.3 卤0.7) mmol / L] in the combined OSAS group were significantly higher than those in the non-OSAS group. The mean heart rate at night and 24 h was significantly lower than that in OSAS group (P 0.05). Multivariate logistic regression analysis showed that neck circumference and age were the risk factors of OSAS in non-obese hypertensive population. The risk of OSAS in patients with neck circumference 鈮，

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