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糖尿病视网膜病变早期患者的视觉对比敏感度变化的观察

发布时间:2018-07-16 22:58
【摘要】:目的 观察糖尿病视网膜病变早期(无明显视网膜病变或仅有微动脉瘤的轻度非增生期)患者的视觉对比敏感度值与相同条件下的正常人群的视觉对比敏感度值相比有否差异。 方法 应用OPTEC6500视功能测试系统分别检查糖尿病视网膜病变早期(无明显视网膜病变或仅有微动脉瘤的轻度非增生期)的患者和相同条件下的正常人各20例4.0眼在空间频率为1.5c/d、3c/d、6c/d、12c/d、18c/d时的空间对比敏感度值,选取1.5c/d和3c/d代表低空间频率,6c/d代表中空间频率,12c/d和18c/d代表高空间频率,测得的视觉对比敏感度值以x±s表示,使用统计软件SPSS11.0,采用t检验,取p0.05为差异有统计学意义做统计学分析。 结果 糖尿病组的对比敏感度值与对照组相比在低频空间1.5c/d和3c/d时,差异无统计学意义(p0.05)。在中频6c/d及12c/d和18c/d的高频区,糖尿病组的对比敏感度值与正常对照组的相比较,差异有统计学意义(p0.05)。 结论 糖尿病视网膜病变早期(无明显视网膜病变或仅有微动脉瘤的轻度非增生期)患者的视觉对比敏感度值与相同条件下的正常人群的视觉对比敏感度值相比降低,应用视觉对比敏感度检查有助于发现糖尿病视网膜病变早期患者的视功能下降,是评价视功能非常敏感的指标。
[Abstract]:Objective to observe the visual contrast sensitivity of patients with early diabetic retinopathy (mild non-proliferative phase with no obvious retinopathy or only microaneurysm) and normal subjects under the same conditions. There is no difference in sensitivity. Methods the OPTEC6500 visual function test system was used to examine the early stage of diabetic retinopathy (mild non-proliferative phase with no obvious retinopathy or only microaneurysm) and the normal subjects under the same condition. Example 4.0 the spatial contrast sensitivity value of 4.0 eyes when the spatial frequency is 1.5 c / d 3 c / d 6 c / d 12 c / d / d 18 c / d, 1.5c/d and 3c/d were selected to represent the low spatial frequency and the middle spatial frequency to represent the middle spatial frequency and the 18c/d to represent the high spatial frequency. The measured visual contrast sensitivity values were expressed as x 卤s, and the statistical software SPSS 11.0 was used, and t test was used. The difference of p0.05 was statistically significant. Results there was no significant difference in contrast sensitivity between diabetic group and control group in low frequency space 1.5c/d and 3c/d (p0.05). In the high frequency region of intermediate frequency 6c/d, 12c/d and 18c/d, the contrast sensitivity of diabetic group was significantly higher than that of normal control group (p0. 05). Conclusion the visual contrast sensitivity of the patients with early diabetic retinopathy (mild non-proliferative phase with no obvious retinopathy or only microaneurysm) was lower than that of the normal subjects under the same condition. The application of visual contrast sensitivity is helpful to find the decline of visual function in early diabetic retinopathy and is a very sensitive index to evaluate visual function.
【学位授予单位】:中国医科大学
【学位级别】:硕士
【学位授予年份】:2010
【分类号】:R774.1

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