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婴幼儿感音性神经性耳聋内耳CT三维重建与临床研究

发布时间:2018-07-17 01:23
【摘要】: 目的 探讨婴幼儿感音性神经性耳聋的临床特点,评估高分辨CT (HRCT)对感音性神经性耳聋的诊断价值和指导治疗的意义。 方法 对20例经脑干听觉诱发电位(ABR)确诊的中重度感音神经性耳聋(SNHL)患者行HRCT螺旋扫描,原始数据采集完后,按层厚0.625mm,重建间隔0.3mm,单侧FOV9.6cm放大重建,再传至工作站行多平面重建(MPR)并利用最小密度投影(Min IP)、容积漫游(VR)及其叠加技术等后处理方法观察内耳结构。 结果 20例感音神经性耳聋患者中有37耳先天性内耳畸形,其中耳蜗未发育1耳、共同腔畸形1耳、不完全分隔Ⅰ型1耳、不完全分隔Ⅱ型即Mondini畸形8耳、前庭和半规管畸形22耳、前庭导水管扩大20耳、内耳道畸形8耳,伴内耳道底发育不全3耳、外耳道骨性闭锁2耳、面神经管异常4耳、前庭窗闭锁2耳、蜗窗闭锁1耳。 结论 婴幼儿感音性神经性耳聋主要病因为先天性内耳发育异常,临床表现不典型,易忽视病情,HRCT螺旋扫描结合后处理技术能清楚显示内耳的结构,为先天性内耳畸形的部位和程度明确其分类,为进一步指导治疗及预后提供有力的依据。
[Abstract]:Objective to investigate the clinical features of sensorineural hearing loss in infants and to evaluate the value of high resolution CT (HRCT) in diagnosis and treatment of sensorineural hearing loss. Methods HRCT spiral scanning was performed in 20 patients with moderate and severe sensorineural hearing loss (SNHL) diagnosed by brainstem auditory evoked potential (ABR). After the original data were collected, the slice thickness was 0.625 mm, the reconstruction interval was 0.3 mm, and the unilateral FOV9.6 cm was amplified and reconstructed. Then it was transferred to the workstation for multiplanar reconstruction (MPR). The inner ear structure was observed by the methods of minimum density projection (Min IP), volume roaming (VR) and superposition technique. Results among the 20 cases of sensorineural deafness, 37 ears were congenital inner ear malformation, including 1 undeveloped cochlea, 1 common cavity malformation, 1 incomplete separation of type I and 8 mondini deformities. 22 ears of vestibular and semicircular canal malformation, 20 ears of vestibular aqueduct enlargement, 8 ears of inner auditory canal malformation, 3 ears of dysplasia of internal auditory meatus, 2 ears of osseous atresia of external auditory meatus, 4 ears of abnormal facial canal, 2 ears of atresia of vestibular window and 1 ear of atresia of cochlear window. Conclusion the main cause of sensorineural deafness in infants is congenital inner ear dysplasia, atypical clinical manifestation, and the structure of inner ear can be clearly displayed by HRCT spiral scan combined with post-processing technique. The classification of congenital inner ear malformation is clear for its location and degree, and it provides a powerful basis for the treatment and prognosis of congenital inner ear malformation.
【学位授予单位】:中国医科大学
【学位级别】:硕士
【学位授予年份】:2010
【分类号】:R764

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