不同波长UVR-B相干作用诱导白内障的特点

发布时间：2018-08-04 08:44

【摘要】：目的研究不同波段UVR-B相干作用引起白内障的特点。方法 6周龄albino Sprague-Dawley大鼠被随机分成四组,每组20只。UVR-B辐射光来自与单色器相连的高压银汞灯,最大的输出能量在300 nm(UVR 300 nm)和310 nm(UVR 310 nm)。每只动物的一只眼被暴露。对照组大鼠暴露于UVR-B的有效生物学剂量是8 k J/m2,只暴露于UVR-B 300 nm,时间70 min;观察组先暴露于UVR-B 300 nm,剂量4 k J/m2,时间35 min;然后同一只眼再暴露于UVR-B 310 nm,剂量42 k J/m2,时间35 min。于暴露后第7天,动物被宰杀。光镜下分析白内障特点。结果对照组的大鼠20只光暴露眼全部发生皮质性白内障。观察组的大鼠20只光暴露眼全部发生皮质联合核性白内障。结论 UVR-B 300 nm光暴露眼可发生皮质性白内障。UVR-B 300 nm、UVR-B 310 nm相干作用引起核性白内障。
[Abstract]:Objective to study the characteristics of cataract induced by coherent interaction of UVR-B in different bands. Methods Sixth-week-old albino Sprague-Dawley rats were randomly divided into four groups. Each group had 20. UVR-B radiation from a high voltage mercury lamp connected to the Monochromator. The maximum output energy was 300 nm (UVR 300nm and 310 nm (UVR 310 nm). One eye of each animal was exposed. The effective biological dose of UVR-B exposure in the control group was 8 kg / m ~ (-2), only UVR-B 300 nm for 70 min, and the observation group was exposed to UVR-B 300 nm at a dose of 4 k J / m ~ (2) for 35 min, and then to UVR-B 310 nm at a dose of 42 k J / m ~ (2) for 35 mins in the same eye. The animals were slaughtered 7 days after exposure. The characteristics of cataract were analyzed under light microscope. Results Cortical cataract occurred in all of the 20 eyes exposed to light in the control group. Conjunctival cortical cataract occurred in all of the 20 eyes exposed to light in the observation group. Conclusion the cortical cataract. UVR-B 300 nm coherent effect of UVR-B 310nm can occur in the eyes exposed to UVR-B 300nm light, and the nuclear cataract can be induced by UVR-B 310nm coherence.
【作者单位】：吉林大学第二医院眼科医院;吉林大学白求恩医学部;
【分类号】：R776.1

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