角膜异物剔除术后感染病原菌分布与预防

发布时间：2018-10-11 19:49

【摘要】：目的探讨角膜异物剔除术后创面感染的病原菌分布及抗菌药物敏感性,为临床预防和治疗提供参考依据。方法选取2011年3月-2013年12月角膜异物剔除术后患者1 174例,采集发生创面感染患者病灶分泌物行病原菌培养和药物敏感试验,对其结果进行分析,采用SPSS 13.0软件进行统计分析。结果手术后患者发生感染共36例,感染率3.07%;检出病原菌34株,检出率94.44%,其中革兰阳性菌18株占52.94%,革兰阴性菌14株占41.18%,真菌2例占5.88%;链球菌属和葡萄球菌属对万古霉素、利奈唑胺敏感,其次对氨苄西林的敏感性也高达94.44%,而对青霉素、红霉素以及替考拉宁的敏感性较低,分别为50.00%、50.00%以及55.56%。结论角膜异物剔除术后创面感染以细菌感染为主,选择敏感抗菌药物可以取得良好治疗效果,对于植物所造成的角膜异物,可酌情给予抗真菌药物进行治疗;此外,在角膜异物剔除术围术期采取必要的措施,预防感染发生。
[Abstract]:Objective to investigate the distribution of pathogenic bacteria and antimicrobial susceptibility of wound infection after corneal foreign body removal, and to provide reference for clinical prevention and treatment. Methods from March 2011 to December 2013, 1 174 patients after corneal foreign body removal were selected and collected from patients with wound infection for pathogen culture and drug sensitivity test. The results were analyzed by SPSS 13.0 software. Results there were 36 cases of infection after operation, the infection rate was 3.07%, 34 strains of pathogenic bacteria were detected, and the detection rate was 94.44%. Among them, 18 strains of Gram-positive bacteria accounted for 52.94, 14 strains of Gram-negative bacteria accounted for 41.18 strains, and 2 cases of fungi accounted for 5.88%, Streptococcus and Staphylococcus were p-vancomycin. The sensitivity of linazolamine to ampicillin was 94.444.The sensitivity to penicillin erythromycin and teicoplanin was 50.0050.00% and 55.56g respectively. Conclusion the wound infection after cornea foreign body culling is mainly bacterial infection. The choice of sensitive antimicrobial agents can obtain good therapeutic effect, and the cornea foreign body caused by plant can be treated with antifungal drugs as appropriate. Take necessary measures to prevent infection during the perioperative period of corneal foreign body removal.
【作者单位】：慈溪市人民医院眼科;
【基金】：浙江省卫生厅基金资助项目(ZW-2010B-039)
【分类号】：R446.5;R779.14

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