应用Smart Plug泪小管塞治疗干眼症的临床观察
发布时间：2018-10-23 21:04
【摘要】：研究背景和目的： 随着社会的进步,人口素质的提高,干眼症的不适症状也越来越受到大家的关注。干眼症的病因十分复杂,目前,临床上仍大多应用人工泪液来治疗。本研究应用Smart Plug(?)目小管塞治疗干眼症,通过封闭患者泪小管以阻止泪液排出,使正常分泌的泪液滞留在眼内,从而改善干眼症状。评价应用Smart Plug泪小管塞治疗干眼症的临床效果。 方法： 收集2009年1月～2010年5月在武警医院眼科门诊的患者作为研究对象,应用Smart Plug泪小管塞治疗干眼症患者42例(84眼),随访5-15月,平均8.3个月,根据SchirmerI试验(SIT)、泪膜破裂时间(TBUT)、角膜荧光素染色(FL),观察临床疗效。 结果： 1.治疗前后SchirmerI试验(SIT)分别为3.41±0.60mm和5.75±0.44mm(P0.05)；2.治疗前后泪膜破裂时间(TBUT)分别为3.75±1.26秒和6.46±1.47秒(P0.05)；3.角膜荧光素染色(FL)评分分别为2.45±0.06分和0.04±0.02分(P0.05)；4.病人主观症状改善。以上检查差异均有统计学意义。 结论： 应用Smart Plug泪小管塞治疗干眼症,封闭患者部分泪小管以阻止泪液的排出,使正常分泌的泪液在眼内滞留,从而改善症状,取得较好的疗效。它既显著简化了操作步骤及难度,也大大降低自体排除率、塞子丢失率及泪道继发感染率。改善了干眼症病人的眼表生理微环境,提高了病人的生活质量。值得进一步临床研究和推广。
[Abstract]:Background and objective: with the progress of society and the improvement of population quality, the discomfort of xerophthalmia has attracted more and more attention. The etiology of xerophthalmia is very complicated. At present, artificial tear is still used in clinic. Smart Plug (? By blocking the lacrimal tubules of the patients to prevent the discharge of tears, the normally secreted tears remain in the eyes, thus improving the xerophthalmia. To evaluate the clinical effect of Smart Plug lacrimal tubule plug in the treatment of xerophthalmia. Methods: from January 2009 to May 2010, 42 patients (84 eyes) with dry eye were treated with Smart Plug lacrimal canaliculus plug. The patients were followed up for 5 to 15 months with an average of 8.3 months. According to SchirmerI test (SIT), tear film rupture time (TBUT), corneal fluorescein staining (FL), to observe the clinical curative effect. Results: 1. The (SIT) of SchirmerI test before and after treatment were 3.41 卤0.60mm and 5.75 卤0.44mm, respectively (P0.05). The tear film rupture time (TBUT) before and after treatment was 3.75 卤1.26 seconds and 6.46 卤1.47 seconds respectively (P0.05). The (FL) scores of corneal fluorescein staining were 2.45 卤0.06 and 0.04 卤0.02 (P0.05), respectively. The patient's subjective symptoms improved. The differences were statistically significant. Conclusion: using Smart Plug lacrimal tubule plug to treat dry eye, blocking part of lacrimal tubules in order to prevent the discharge of tear, so that the normal secretion of tears in the eyes, so as to improve the symptoms and obtain better curative effect. It not only simplifies the procedure and difficulty, but also reduces the rate of self exclusion, plug loss and secondary infection of lacrimal duct. The physiological microenvironment of dry eye patients was improved and the quality of life was improved. It is worth further clinical research and promotion.
【学位授予单位】：山东大学
【学位级别】：硕士
【学位授予年份】：2011
【分类号】：R777.2
本文编号：2290459
[Abstract]:Background and objective: with the progress of society and the improvement of population quality, the discomfort of xerophthalmia has attracted more and more attention. The etiology of xerophthalmia is very complicated. At present, artificial tear is still used in clinic. Smart Plug (? By blocking the lacrimal tubules of the patients to prevent the discharge of tears, the normally secreted tears remain in the eyes, thus improving the xerophthalmia. To evaluate the clinical effect of Smart Plug lacrimal tubule plug in the treatment of xerophthalmia. Methods: from January 2009 to May 2010, 42 patients (84 eyes) with dry eye were treated with Smart Plug lacrimal canaliculus plug. The patients were followed up for 5 to 15 months with an average of 8.3 months. According to SchirmerI test (SIT), tear film rupture time (TBUT), corneal fluorescein staining (FL), to observe the clinical curative effect. Results: 1. The (SIT) of SchirmerI test before and after treatment were 3.41 卤0.60mm and 5.75 卤0.44mm, respectively (P0.05). The tear film rupture time (TBUT) before and after treatment was 3.75 卤1.26 seconds and 6.46 卤1.47 seconds respectively (P0.05). The (FL) scores of corneal fluorescein staining were 2.45 卤0.06 and 0.04 卤0.02 (P0.05), respectively. The patient's subjective symptoms improved. The differences were statistically significant. Conclusion: using Smart Plug lacrimal tubule plug to treat dry eye, blocking part of lacrimal tubules in order to prevent the discharge of tear, so that the normal secretion of tears in the eyes, so as to improve the symptoms and obtain better curative effect. It not only simplifies the procedure and difficulty, but also reduces the rate of self exclusion, plug loss and secondary infection of lacrimal duct. The physiological microenvironment of dry eye patients was improved and the quality of life was improved. It is worth further clinical research and promotion.
【学位授予单位】：山东大学
【学位级别】：硕士
【学位授予年份】：2011
【分类号】：R777.2
【参考文献】
相关期刊论文 前10条
1 宋颖,周绍荣,张琳;干眼的诊治及其在眼科手术中的影响[J];国外医学(眼科学分册);2004年03期
2 韦青松;王伯钧;陈玉新;潘春辉;欧玉伦;;眼科门诊干眼症的流行病学调查[J];广西医科大学学报;2008年01期
3 宋秀君;庞润晖;;干眼与相关细胞因子的研究进展[J];河北医药;2006年12期
4 严厉;顾宝文;司马晶;王晖;邓惠芳;;眼科门诊患者中干眼症的流行病学调查[J];解剖与临床;2006年03期
5 何昆,李萌;腮腺导管转位结膜囊内治疗干眼症13例体会[J];临床军医杂志;2003年06期
6 刘祖国,钟铮,梁凌毅;干眼的诊治[J];食品与药品;2005年05期
7 闫玲,张丽彩,初培莲,万海青;滋肾润目丸治疗干眼症临床观察[J];山东中医杂志;2005年10期
8 朱萍;干眼患者临床症状分析[J];实用医学杂志;2005年10期
9 王梦，，钱红美，孙奋治，宋俊生;“南方人工泪液”对泪膜破裂时间的影响[J];铁道医学;1994年04期
10 李晓新,朱正宏,俞光岩,张雷,彭科凤;自体颌下腺移植治疗角结膜干燥症术后泪液成份分析[J];现代口腔医学杂志;2002年03期
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