高度近视合并白内障植入不同人工晶状体的临床分析
发布时间：2018-11-06 11:28
【摘要】：一、高度近视合并白内障植入三种不同人工晶状体的临床分析 目的：比较高度近视合并白内障超声乳化吸除分别植入3种不同人工晶状体(intraocular lens IOL)的临床效果。 方法：回顾性系列病例研究。回顾性分析天津市眼科医院白内障中心2008年5月至2009年6月高度近视合并白内障患者68眼行超声乳化白内障吸除联合IOL植入术后3mo的随访资料。患者分别植入一片式三襻亲水性丙烯酸酯IOL(Bigbag, ZEISS)、一片式C形襻亲水性丙烯酸酯IOL(620H, Rayner),一片式C形襻亲水性丙烯酸酯IOL (HQ201-hep)。使用Pentacam三维眼前节测量系统采集各眼Scheimpflug图像,测量散瞳后前房深度,使用Image-pro plus 6.0图像分析得出IOL的倾斜度和偏心值。使用iTrace视觉分析仪测量5mm瞳孔直径下的眼内球差。检测术后IOL眼实际屈光度与靶屈光度差异。满足正态分布和方差齐性的行单因素方差分析,采用SNK-q检验进行组间两两比较。结果：3组间前房深度比较有统计学意义(F=50.74,P0.05)。实际屈光度与靶屈光度的误差,3组比较无统计学意义(F=1.391,P0.05)。IOL偏心与倾斜在水平和垂直方向上的数值差异均无统计学意义(P0.05)。3组间5mm瞳孔直径下眼内球差比较无统计学意义(F=2.096,P0.05)。未见后囊膜混浊,黄斑水肿,视网膜脱离发生。 结论：3种不同IOL均可用于高度近视合并白内障患者,但各有其优越性和局限性。 二、高度近视合并白内障植入不同多焦点人工晶状体视觉质量分析 目的：比较高度近视合并白内障超声乳化吸除分别植入2种不同多焦点人工晶状体(multifocal intraocular lens, MIOL)的视觉质量。 方法：回顾性系列病例研究。回顾性分析天津市眼科医院白内障中心2009年2月至2010年6月高度近视合并白内障40眼行超声乳化白内障吸除联合IOL植入术后3mo的随访资料。患者分别植入AR40e(SENSAR, AMO)单焦点IOL(monofocal/single-focal intraocular lens, SIOL) 20眼、REZOOM (NXG1, AMO)折射型MIOL8眼, TECNIS ZMA00 (AMO)衍射型MIOL12眼。使用Snellen标准视力表(5m)及Colenbrander Mixed Contrast Card Set视力测试卡(0.4m)分别测量裸眼远近视力,最佳矫正远视力及最佳矫正远视力下近视力。使用iTrace波前像差仪测量5mm瞳孔直径下的眼内像差及调制传递函数(modulationtransfer function, MTF)曲线。满足正态分布和方差齐性的行单因素方差分析,采用SNK-q检验进行组间两两比较。不满足的行K-W秩和检验。 结果：3组患者术后3个月裸眼远视力,最佳矫正远视力下近视力比较有统计学意义(P0.05)。裸眼近视力,最佳矫正远视力差异无统计学意义(P0.05)。3组患者在瞳孔5mm直径时,眼内球差差异有统计学意义(P0.05),眼内彗差及三叶草比较无统计学意义(p0.05)。MTF值在5/10/15cpd时差异有统计学意义(p0.05)。 结论：高度近视合并白内障患者更适合植入衍射型MIOL。
[Abstract]:1. Clinical analysis of three different kinds of intraocular lens implantation in high myopia with cataract objective: to compare the clinical effects of phacoemulsification and implantation of three different intraocular lens (intraocular lens IOL) in high myopia with cataract. Methods: a series of retrospective case studies. The follow-up data of 68 eyes of patients with high myopia and cataract after phacoemulsification combined with IOL implantation in Tianjin Eye Hospital from May 2008 to June 2009 were analyzed retrospectively. Patients were implanted with a three-loop hydrophilic acrylate (IOL (Bigbag, ZEISS),) and a C-shaped loop (IOL) (620H, Rayner), / C) IOL (HQ201-hep). The Pentacam 3D anterior segment measurement system was used to collect the Scheimpflug images of each eye, and the anterior chamber depth after pupil dilation was measured. The tilt and eccentricity of IOL were obtained by Image-pro plus 6.0 image analysis. ITrace visual analyzer was used to measure the intraocular spherical aberration under the pupil diameter of 5mm. The difference between the actual diopter and target diopter of IOL eyes after operation was detected. Univariate ANOVA satisfying normal distribution and homogeneity of variance was performed, and SNK-q test was used to compare the two groups. Results: there was significant difference in anterior chamber depth among the three groups (P 0.05). There was no significant difference between the actual diopter and target diopter in the three groups (F = 1.391, P < 0.05). There was no significant difference between). IOL eccentricity and tilt in horizontal and vertical direction (P0.05). There was no significant difference in intraocular spherical aberration under the pupil diameter of 5mm among the three groups (FF2.096). No posterior capsule opacification, macular edema, retinal detachment occurred. Conclusion: three kinds of IOL can be used in high myopia patients with cataract, but each has its advantages and limitations. Visual quality Analysis of different Multi-focus IOL implantation in High myopia with Cataract objective: to compare the phacoemulsification and implantation of two kinds of multi-focus intraocular lens (multifocal intraocular lens,) in high myopia with cataract implantation. MIOL) visual quality. Methods: a series of retrospective case studies. The follow-up data of 40 eyes with high myopia combined with cataract after phacoemulsification and IOL implantation in Tianjin Eye Hospital from February 2009 to June 2010 were analyzed retrospectively. AR40e (SENSAR, AMO) single focus IOL (monofocal/single-focal intraocular lens, SIOL) 20 eyes) refracted MIOL8 eyes and TECNIS ZMA00 (AMO) diffractive MIOL12 eyes were implanted respectively. Snellen standard visual acuity chart (5m) and Colenbrander Mixed Contrast Card Set visual acuity test card (0.4m) were used to measure the uncorrected far and near visual acuity, the best corrected far visual acuity and the best corrected far visual acuity. The intraocular aberration and modulation transfer function (modulationtransfer function, MTF) curves of 5mm pupil diameter were measured by iTrace wavefront aberration instrument. Univariate ANOVA satisfying normal distribution and homogeneity of variance was performed, and SNK-q test was used to compare the two groups. Dissatisfied with the K-W rank sum test. Results: three months after operation, the uncorrected distant visual acuity and the near visual acuity under the best corrected distant visual acuity were statistically significant (P0.05). There was no significant difference in uncorrected near visual acuity and best corrected far visual acuity (P0.05). There were significant differences in intraocular spherical aberration in pupil 5mm diameter in 3 groups (P0.05). There was no significant difference in intraocular coma and clover (p0. 05). MTF in 5/10/15cpd). Conclusion: high myopia with cataract is more suitable for the implantation of diffractive MIOL..
【学位授予单位】：天津医科大学
【学位级别】：硕士
【学位授予年份】：2011
【分类号】：R779.66
本文编号：2314137
[Abstract]:1. Clinical analysis of three different kinds of intraocular lens implantation in high myopia with cataract objective: to compare the clinical effects of phacoemulsification and implantation of three different intraocular lens (intraocular lens IOL) in high myopia with cataract. Methods: a series of retrospective case studies. The follow-up data of 68 eyes of patients with high myopia and cataract after phacoemulsification combined with IOL implantation in Tianjin Eye Hospital from May 2008 to June 2009 were analyzed retrospectively. Patients were implanted with a three-loop hydrophilic acrylate (IOL (Bigbag, ZEISS),) and a C-shaped loop (IOL) (620H, Rayner), / C) IOL (HQ201-hep). The Pentacam 3D anterior segment measurement system was used to collect the Scheimpflug images of each eye, and the anterior chamber depth after pupil dilation was measured. The tilt and eccentricity of IOL were obtained by Image-pro plus 6.0 image analysis. ITrace visual analyzer was used to measure the intraocular spherical aberration under the pupil diameter of 5mm. The difference between the actual diopter and target diopter of IOL eyes after operation was detected. Univariate ANOVA satisfying normal distribution and homogeneity of variance was performed, and SNK-q test was used to compare the two groups. Results: there was significant difference in anterior chamber depth among the three groups (P 0.05). There was no significant difference between the actual diopter and target diopter in the three groups (F = 1.391, P < 0.05). There was no significant difference between). IOL eccentricity and tilt in horizontal and vertical direction (P0.05). There was no significant difference in intraocular spherical aberration under the pupil diameter of 5mm among the three groups (FF2.096). No posterior capsule opacification, macular edema, retinal detachment occurred. Conclusion: three kinds of IOL can be used in high myopia patients with cataract, but each has its advantages and limitations. Visual quality Analysis of different Multi-focus IOL implantation in High myopia with Cataract objective: to compare the phacoemulsification and implantation of two kinds of multi-focus intraocular lens (multifocal intraocular lens,) in high myopia with cataract implantation. MIOL) visual quality. Methods: a series of retrospective case studies. The follow-up data of 40 eyes with high myopia combined with cataract after phacoemulsification and IOL implantation in Tianjin Eye Hospital from February 2009 to June 2010 were analyzed retrospectively. AR40e (SENSAR, AMO) single focus IOL (monofocal/single-focal intraocular lens, SIOL) 20 eyes) refracted MIOL8 eyes and TECNIS ZMA00 (AMO) diffractive MIOL12 eyes were implanted respectively. Snellen standard visual acuity chart (5m) and Colenbrander Mixed Contrast Card Set visual acuity test card (0.4m) were used to measure the uncorrected far and near visual acuity, the best corrected far visual acuity and the best corrected far visual acuity. The intraocular aberration and modulation transfer function (modulationtransfer function, MTF) curves of 5mm pupil diameter were measured by iTrace wavefront aberration instrument. Univariate ANOVA satisfying normal distribution and homogeneity of variance was performed, and SNK-q test was used to compare the two groups. Dissatisfied with the K-W rank sum test. Results: three months after operation, the uncorrected distant visual acuity and the near visual acuity under the best corrected distant visual acuity were statistically significant (P0.05). There was no significant difference in uncorrected near visual acuity and best corrected far visual acuity (P0.05). There were significant differences in intraocular spherical aberration in pupil 5mm diameter in 3 groups (P0.05). There was no significant difference in intraocular coma and clover (p0. 05). MTF in 5/10/15cpd). Conclusion: high myopia with cataract is more suitable for the implantation of diffractive MIOL..
【学位授予单位】：天津医科大学
【学位级别】：硕士
【学位授予年份】：2011
【分类号】：R779.66
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