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鼻腔肿瘤调强放疗舌的位置与剂量学研究

发布时间:2018-11-20 10:43
【摘要】:目的:探讨鼻腔内肿瘤调强放疗时舌的位置与剂量学关系。方法:对5例2011-11-02-2012-08-31华中科技大学同济医学院附属同济医院经病理和影像确诊局限于鼻腔内肿瘤患者,在治疗计划系统中测量舌到硬腭的距离并计算其剂量,测量5例患者142次治疗摆位完成后锥形束CT(conebeam CT,CBCT)影像中的舌到硬腭的距离,并在治疗计划系统中模拟计算舌在该位置的剂量。结果:治疗计划定位时舌到硬腭的距离为0.00~1.10cm,治疗摆位时为0.00~0.95cm,治疗时舌的位置与定位时的重合率仅为3.52%,各例患者舌位置差异均值在0.10~0.35cm,剂量差异最大可达30.01Gy。结论:局限于鼻腔内肿瘤调强放疗时,作为毗邻器官舌的位置不易重复和固定,导致剂量差异。建议采用适当形状和组织等密度材料的压舌板予以固定,使舌远离硬腭以减小其所受剂量。
[Abstract]:Objective: to investigate the relationship between tongue position and dose during intensity-modulated radiotherapy (IMRT) for nasal tumors. Methods: five cases of Tongji Hospital affiliated to Tongji Medical College, Tongji University of Science and Technology, Huazhong University of Science and Technology, were selected and confirmed by pathology and imaging. The distance between tongue and hard palate was measured and the dose was calculated in the treatment planning system. The distance between tongue and hard palate in CT (conebeam CT,CBCT images of 5 patients was measured and the dose of tongue in this position was simulated in the treatment planning system. Results: the distance between the tongue and the hard palate was 0.0010 cm and 0.000.95 cm respectively. The coincidence rate between the position of the tongue and the position of the hard palate was only 3.52 cm. The mean value of the position of the tongue was 0.10 ~ 0.35 cm. The maximum dose difference was 30.01Gy. Conclusion: it is difficult to repeat and fix the position of tongue as an adjoining organ during intensity-modulated radiotherapy in nasal cavity, which leads to the difference of dose. It is suggested that the tongue press plate with proper shape and tissue density should be used to keep the tongue away from the hard palate in order to reduce its dose.
【作者单位】: 华中科技大学同济医学院附属同济医院肿瘤科;
【分类号】:R739.62

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