飞秒准分子激光原位角膜磨镶术后1年角膜后表面高度变化

发布时间：2018-11-27 20:19

【摘要】：目的:采用Allegro Oculyzer眼前节诊断系统探讨飞秒准分子激光原位角膜磨镶术矫正近视术后1年内角膜后表面高度变化规律。方法:选择行飞秒激光LASIK矫正近视(术前等效球镜-10.63~-1.63 D)患者45例(90只眼),采用Allegro Oculyzer眼前节诊断系统分别在术前、术后1、3、6个月及1年对术眼进行眼前节三维图像采集,分别测量角膜中央后表面高度、角膜最薄点厚度并计算角膜后表面高度差异。采用重复测量的方差分析和Pearson相关分析。结果:飞秒激光LASIK术前与术后不同随访时间点角膜后表面高度进行重复测量的方差分析示,差异无统计学意义(F=1.50,P0.05)。飞秒激光LASIK术后1、3、6个月及1年角膜后表面高度差异进行重复测量的方差分析,差异无统计学意义(F=1.47,P0.05)。术前及术后不同随访时间点角膜最薄点厚度进行重复测量的方差分析,差异有统计学意义(F=369.10,P0.01)。飞秒激光LASIK术后不同随访时间角膜后表面高度与SE、AD、RBT、AP/TCT及"(角膜瓣厚度+切削厚度)/术前角膜最薄点厚度",无相关关系(P0.05)。结论:严格掌握手术适应证的飞秒LASIK术后角膜后表面稳定性良好,角膜后表面高度并未发生明显的变化;角膜最薄点厚度逐渐增加并于术后3个月趋于稳定。
[Abstract]:Objective: to investigate the changes of corneal posterior surface height within 1 year after correction of myopia by femtosecond laser in situ keratomileusis with Allegro Oculyzer anterior segment diagnostic system. Methods: Forty-five patients (90 eyes) with myopia were treated with femtosecond laser LASIK (preoperative equivalent spherical mirror -10.63 ~ 1.63 D). The diagnosis system of anterior segment of Allegro Oculyzer was used to diagnose myopia before and after operation. Three dimensional images of anterior segment were collected in 6 months and 1 year respectively. The height of the central posterior surface of the cornea and the thickness of the thinnest point of the cornea were measured and the difference of the height of the posterior surface of the cornea was calculated. ANOVA and Pearson correlation analysis were used. Results: there was no significant difference between femtosecond laser LASIK before and after the repeated measurement of corneal posterior surface height at different follow-up time points (F1. 50 P 0. 05). Femtosecond laser LASIK was used to analyze the difference of corneal posterior surface height between 3 months, 6 months and 1 year after operation. There was no significant difference (P 0.05). The analysis of variance of the thickness of the thinnest point of cornea at different follow-up time points before and after operation showed significant difference (F _ (369.10) P _ (0.01). There was no correlation between corneal posterior surface height and SE,AD,RBT,AP/TCT and "(corneal flap thickness) / preoperative corneal thinnest point thickness" at different follow-up time after femtosecond laser LASIK (P0.05). Conclusion: Femtosecond LASIK (Femtosecond LASIK) has good posterior corneal surface stability and no obvious change in corneal posterior surface height, and the thickness of the thinnest point increases gradually and becomes stable 3 months after operation.
【作者单位】：南方医科大学附属南海医院眼科;
【分类号】：R779.63

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