扩散加权成像鉴别诊断鼻咽癌和鼻咽部淋巴瘤

发布时间：2018-12-11 13:42

【摘要】：目的探讨DWI鉴别诊断鼻咽癌(NPC)及鼻咽部淋巴瘤(NPL)的价值。方法回顾性分析经病理证实的22例NPC和27例NPL的平扫、增强MRI及DWI图像,对比分析两者的平均ADC值和病灶与未受侵翼外肌ADC值的比值(rADC值),应用ROC曲线分析以ADC值、rADC值鉴别诊断NPC与NPL的效能。结果 NPC与NPL均于T1WI呈等或稍低信号、T2WI呈稍高信号。NPC于DWI(b=1000s/mm2)上呈稍高信号、ADC图上呈等低信号,NPL于DWI(b=1000s/mm2)上呈高信号、ADC图上呈低信号。NPC组ADC值为(842.34±94.66)×10-6 mm2/s、rADC值为0.74±0.08。NPL组ADC值为(652.15±83.47)×10-6 mm2/s、rADC值为0.56±0.08。两组病灶ADC值、rADC值的差异均具有统计学意义(P均0.001)。应用ADC值鉴别NPC与NPL的曲线下面积为0.943,最佳鉴别阈值为736.5×10-6 mm2/s,敏感度为90.9%,特异度为85.2%;应用rADC值进行鉴别的曲线下面积为0.951,最佳鉴别阈值为634.0×10-6 mm2/s,敏感度为95.5%,特异度为81.5%。结论 DWI、ADC值及rADC值有助于鉴别诊断NPC与NPL。
[Abstract]:Objective to evaluate the value of DWI in differential diagnosis of nasopharyngeal carcinoma (NPC) (NPC) and nasopharyngeal lymphoma (NPL). Methods 22 cases of pathologically proved NPC and 27 cases of NPL were analyzed retrospectively. The average ADC value and rADC value of the lesion and the ADC value of the non-invading pterygoid muscle were compared with those of MRI and DWI images. The ADC value was analyzed by ROC curve. The effectiveness of rADC value in differential diagnosis of NPC and NPL. Results both NPC and NPL showed equal or slightly low signal intensity in T1WI, T2WI showed slightly high signal, NPC showed slightly high signal on DWI (b=1000s/mm2), ADC showed isohypo signal and NPL DWI (b=1000s/mm2) showed high signal. The ADC value of NPC group was (842.34 卤94.66) 脳 10 ~ (-6) mm2/s,rADC. The ADC value of NPC group was (652.15 卤83.47) 脳 10 ~ (-6) mm2/s,rADC = 0.56 卤0.08. There were significant differences in ADC and rADC between the two groups (P 0.001). The area under the curve of NPC and NPL was 0.943 by using ADC value, the optimum threshold was 736.5 脳 10 ~ (-6) mm2/s, the sensitivity was 90.9 and the specificity was 85.2; The area under the curve was 0.951, the optimum threshold was 634.0 脳 10 ~ (-6) mm2/s, sensitivity was 95.55.The specificity was 81.5%. Conclusion DWI,ADC and rADC are helpful in differential diagnosis of NPC and NPL..
【作者单位】：郑州大学第一附属医院磁共振科;
【分类号】：R445.2;R739.6

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