联合超声乳化白内障吸除术的玻璃体切除术对糖尿病视网膜病变患者泪膜的影响
发布时间：2018-12-12 02:08
【摘要】： 目的 初步探讨玻璃切除手术对于糖尿病视网膜病变患者眼表及泪膜功能的影响,以及术后泪膜功能的恢复情况。 方法 按照本研究的纳入和排除标准,观察了35例(42眼)行玻璃体切除手术的患者,玻璃体切除手术后应用妥布霉素地塞米松眼液、眼膏,必要时联合应用散瞳眼液和降眼压眼液。分别于术前3d,术后7d、14d及30d详细询问患者是否存在不适症状(干涩感、异物感、烧灼感)并评分,并行泪膜破裂时间(Break-Up Time,BUT)、角膜荧光素染色(Cornea Fluorescein Staining, CFS)检查及评分、泪液分泌试验(Schirmer test, ST).对检查结果进行统计学分析。 结果 与手术前相比,术后第7d患者的不适症状评分和CFS评分较术前显著增加(P0.05),无法形成稳定的泪膜,ST显著增加。术后第7d、14d的不适症状评分较术前增加且差异性显著(P0.05),至术后30d恢复至术前水平(P0.05)。术后第7d、14d,BUT较术前减少且差异性显著(P0.05),ST和CFS较术前增加且差异性显著(P0.05)。至术后30d,BUT和CFS较术前仍减少且差异性显著(P0.05),ST与术前相比未见显著性差异(P0.05),恢复至术前水平。 结论 玻璃体切除手术显著影响泪膜的稳定性。至术后30d,只有泪膜的部分功能指标恢复至术前水平。
[Abstract]:Objective to investigate the effect of vitrectomy on the function of ocular surface and tear film in patients with diabetic retinopathy and the recovery of lacrimal film function after vitrectomy. Methods according to the criteria of inclusion and exclusion, 35 cases (42 eyes) of vitrectomy were treated with tobramycin dexamethasone eye fluid and ointment after vitrectomy. Use mydriatic and hypotensive eye drops when necessary. At 3 days before operation, 14 days after operation and 30 days after operation, the patients were asked whether there were any symptoms (dry, foreign body sensation, burning sensation) and score, lacrimal film rupture time (Break-Up Time,BUT), corneal fluorescein staining (Cornea Fluorescein Staining, CFS) examination and score, tear secretion test (Schirmer test, ST). The results were analyzed statistically. Results compared with those before operation, the scores of discomfort symptom and CFS were significantly increased on the 7th day after operation (P0.05), but there was no stable tear film, and ST was significantly increased. The scores of discomfort symptoms increased significantly on the 7th day after operation (P0.05), and recovered to the preoperative level 30 days after operation (P0.05). On the 7th day after operation, but decreased and the difference was significant (P0.05), ST and CFS were significantly higher than those before operation (P0.05). At 30 days after operation, but and CFS still decreased and the difference was significant (P0.05), ST compared with pre-operation no significant difference (P0.05), recovered to the preoperative level. Conclusion vitrectomy has a significant effect on the stability of tear film. At 30 days after operation, only some of the functional indexes of tear film recovered to the preoperative level.
【学位授予单位】：中国医科大学
【学位级别】：硕士
【学位授予年份】：2010
【分类号】：R779.6
本文编号：2373691
[Abstract]:Objective to investigate the effect of vitrectomy on the function of ocular surface and tear film in patients with diabetic retinopathy and the recovery of lacrimal film function after vitrectomy. Methods according to the criteria of inclusion and exclusion, 35 cases (42 eyes) of vitrectomy were treated with tobramycin dexamethasone eye fluid and ointment after vitrectomy. Use mydriatic and hypotensive eye drops when necessary. At 3 days before operation, 14 days after operation and 30 days after operation, the patients were asked whether there were any symptoms (dry, foreign body sensation, burning sensation) and score, lacrimal film rupture time (Break-Up Time,BUT), corneal fluorescein staining (Cornea Fluorescein Staining, CFS) examination and score, tear secretion test (Schirmer test, ST). The results were analyzed statistically. Results compared with those before operation, the scores of discomfort symptom and CFS were significantly increased on the 7th day after operation (P0.05), but there was no stable tear film, and ST was significantly increased. The scores of discomfort symptoms increased significantly on the 7th day after operation (P0.05), and recovered to the preoperative level 30 days after operation (P0.05). On the 7th day after operation, but decreased and the difference was significant (P0.05), ST and CFS were significantly higher than those before operation (P0.05). At 30 days after operation, but and CFS still decreased and the difference was significant (P0.05), ST compared with pre-operation no significant difference (P0.05), recovered to the preoperative level. Conclusion vitrectomy has a significant effect on the stability of tear film. At 30 days after operation, only some of the functional indexes of tear film recovered to the preoperative level.
【学位授予单位】：中国医科大学
【学位级别】：硕士
【学位授予年份】：2010
【分类号】：R779.6
【参考文献】
相关期刊论文 前6条
1 宋颖,周绍荣,张琳;干眼的诊治及其在眼科手术中的影响[J];国外医学(眼科学分册);2004年03期
2 张黎明,陈辉;部分视网膜切除在复杂性视网膜脱离术中的应用[J];实用临床医药杂志;2004年06期
3 马晓昀,邹俊,王文清,尹茶仙,陈国辉;3.5mm和5.5mm切口超声乳化白内障吸除术后角膜地形图分析[J];中华眼科杂志;2002年01期
4 刘祖国,罗丽辉,张振平,程冰,郑丹莹,陈伟蓉,林振德,杨文辉,刘奕志,张梅,肖启国,陈家祺;超声乳化白内障吸除术后泪膜的变化[J];中华眼科杂志;2002年05期
5 刘祖国;干眼的诊断[J];中华眼科杂志;2002年05期
6 徐建江,孙兴怀,陈宇虹,张朝然;白内障超声乳化手术对眼表的影响[J];中国实用眼科杂志;2005年08期
，本文编号：2373691
本文链接：https://www.wllwen.com/yixuelunwen/yank/2373691.html
最近更新
教材专著
