阻塞性睡眠呼吸暂停综合征患者夜间睡眠对日间嗜睡的影响

发布时间：2018-12-13 16:10

【摘要】：目的:探讨阻塞性睡眠呼吸暂停综合征患者(OSAS)夜间睡眠对日间嗜睡的影响。 方法:在我们的研究中依次纳入AHI5次/小时的OSAS患者182例,依据多次日间睡眠潜伏期测试(MSLT)和Epworth嗜睡量表(ESS)资料进行日间嗜睡分组:①日间嗜睡组(EDS组,n=32):ESS10分,MSLT5分钟;②非日间嗜睡组(No-EDS组,n=48):ESS≤10分,MSLT10分钟。 结果:与No-EDS患者比较,EDS患者有以下特征:1)AHI更大,血氧饱和度95%的时间更长,在REM及NREM睡眠期平均血氧饱和度,整夜最低血氧和平均血氧饱和度更低;2)睡眠潜伏期和REM睡眠潜伏期更短,总的睡眠时间更长和睡眠效率更高;3)微觉醒指数更高,1期睡眠持续时间更长,慢波睡眠比例降低。此外通过逐步logistic回归分析发现只有夜间睡眠的微觉醒指数、血氧饱和度95%的时间、REM睡眠潜伏期是日间嗜睡的独立预测因子。 结论:研究结果表明有日间嗜睡的OSAS患者夜间睡眠具有以下特征:1)严重的呼吸暂停/低通气和低氧血症,2)片段化睡眠,3)睡眠质量差和睡眠压力高。
[Abstract]:Objective: to investigate the effect of (OSAS) sleep on daytime sleepiness in patients with obstructive sleep apnea syndrome (OSAS). Methods: one hundred and eighty-two OSAS patients with AHI5 / hour were included in our study. According to (MSLT) and (ESS) data of multiple daytime sleep latency test, daytime sleepiness was divided into 1 day sleepiness group (EDS group), 1 day somnolence group (EDS group), 1 day sleepiness group (EDS group), and 1 day sleepiness group (EDS group). ESS10 score, MSLT5 minute; 2 Non-daytime sleepiness group (No-EDS group, n = 48): ESS 鈮，

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