从补肾活血论治老年性听力损失的疗效及对患者生活质量影响的观察

发布时间：2019-05-05 14:33

【摘要】：目的：观察从补肾活血法治疗老年性听力损失的临床疗效及对患者生活质量影响。方法：根据随机,对照原则,将符合观察标准的患者随机分为两组,治疗组给予六味地黄丸加骨碎补、丹参加味方,对照组给予中成药耳聋左慈丸,两组均服药30天,记录症状体征,采用老年人听力残疾量表进行生活质量评估。结果：研究结果显示：两组患者的纯音听阈测试听力损失程度、言语分辨率组内治疗后对比,两组间对比,经统计学处理,P0.05,差异无统计学意义,提示六味地黄丸加骨碎补、丹参加味方和耳聋左慈丸改善纯音听阈测试听力损失程度、言语分辨率均无效,且两组间无明显差异；治疗组患者的伴随症状耳鸣如蝉进行组内治疗前后对比,P0.05,提示六味地黄丸加骨碎补、丹参加味方改善伴随症状耳鸣如蝉都有效,两组间治疗第30天治疗效果对比有统对比计学意义,P0.05,提示六味地黄丸加骨碎补、丹参加味方改善伴随症状耳鸣如蝉疗效优于耳聋左慈丸；两组患者生活质量的统计分析,进行组内治疗后对比,P0.05,提示六味地黄丸加骨碎补、丹参加味和耳聋左慈丸改善患者生活质量都有效,两组对比,P0.05,提示六味地黄丸加骨碎补、丹参加味改善患者生活质量尤其情感障碍方面的疗效优于耳聋左慈丸。结论：(1)六味地黄丸加骨碎补、丹参加味和耳聋左慈丸改善老年性听力损失纯音听阈测试听力损失程度、言语分辨率均无效。 (2)六味地黄丸加骨碎补、丹参加味和耳聋左慈丸改善老年性听力损失伴随症状耳鸣如蝉均有效,六味地黄丸加骨碎补、丹参加味方优于耳聋左慈丸。 (3)六味地黄丸加骨碎补、丹参加味方和耳聋左慈丸改善老年性听力损失患者生活质量均有效,六味地黄丸加骨碎补、丹参加味方尤其在改善情感障碍方面优于耳聋左慈丸。 (4)生活质量可作为判定老年性听力损失的疗效指标之一,老年人听力残疾量表适用于判定老年性听力损失患者的生活质量。
[Abstract]:Objective: to observe the clinical efficacy and quality of life of senile hearing loss treated by tonifying kidney and activating blood circulation. Methods: according to the principle of randomization and control, the patients who met the observation criteria were randomly divided into two groups. The treatment group was treated with Liuwei Dihuang Pill plus Bushuhuanbu, Danjianwei recipe, and the control group was given Zuo Ciwan, a traditional Chinese patent medicine. The two groups took medicine for 30 days. The symptoms and signs were recorded and the quality of life was assessed with the hearing disability scale for the elderly. Results: the results showed that there was no significant difference between the two groups in pure tone hearing loss test, speech resolution group after treatment, and between the two groups, after statistical treatment, P 0.05, there was no significant difference between the two groups (P > 0.05), but no significant difference was found between the two groups (P < 0.05). It was suggested that Liuwei Dihuang Pill with bone crushing, Dan participating in Weifang and Deafu Zuoci Pill could improve the hearing loss of pure tone hearing threshold test, and the speech resolution was ineffective, and there was no significant difference between the two groups. In the treatment group, patients with symptoms such as cicadas were compared before and after treatment, P 0.05, suggesting that Liuwei Dihuang Pill plus bone fragmentation, Danjiaofangfang to improve the symptoms accompanied by tinnitus such as cicadas are effective, There was a systematic comparison of therapeutic effects between the two groups on the 30th day, P 0.05, suggesting that Liuwei Dihuang Pill plus bone fragmentation, Danjianwei recipe to improve symptoms accompanied by tinnitus such as cicadas curative effect is better than Deafu Zuo Ciwan; The statistical analysis of the quality of life of the two groups was carried out after treatment, P 0.05, suggesting that Liuwei Dihuang Pill plus Bone fragmentation, Salvia miltiorrhiza modified and Deafness Zuo Ciwan were effective in improving the quality of life of the patients, the comparison between the two groups, P0.05, It is suggested that Liuwei Dihuang Pill plus bone crushing and salvia miltiorrhiza can improve the quality of life, especially emotional disorder, and the curative effect is better than Deafu Zuo Ciwan. Conclusion: (1) Liuwei Dihuang Pill, Danshen decoction and Deafang Zuoci Pill can improve the degree of hearing loss by pure tone audiometry test, and the speech resolution is ineffective. (2) Liuwei Dihuang Pill plus Bushuhuanbu, Danshen Jiawei and Ershuangzuoci Pill were effective in improving the symptoms of senile hearing loss accompanied by tinnitus such as cicadas, and Liuwei Dihuang Pill plus Bone crushing and Buping, Danjianwei recipe was superior to Deafang Zuo Ciwan in improving senile hearing loss. (3) Liuwei Dihuang Pill plus Bushuhuanbu, Dan participating in Weifang and Ershuangzuoci Pill were effective in improving the quality of life of the patients with senile hearing loss. Liuweidihuang Pill plus Bushuhuanbu, Danjianwei decoction was better than Deafang Zuoci Pill in improving affective disorder, especially in improving emotional disorder. (4) the quality of life can be used as one of the effective indexes to determine the hearing loss in the elderly, and the hearing disability scale for the elderly can be used to determine the quality of life of the patients with hearing loss in the elderly.
【学位授予单位】：成都中医药大学
【学位级别】：硕士
【学位授予年份】：2011
【分类号】：R764

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