滋肾健脾法联合光动力疗法治疗脉络膜新生血管的效果

发布时间：2019-05-11 04:29

【摘要】：目的观察滋肾健脾法联合光动力疗法(PDT)治疗脉络膜新生血管(CNV)的临床效果。方法将27例30眼CNV患者分为两组,对照组13例15眼单纯采用PDT治疗;观察组14例15眼在PDT治疗的基础上,以滋肾健脾为治则采用中药辨证论治。观察并比较两组患者视力、渗漏情况、黄斑中心凹层间厚度变化等情况。结果治疗后1、3、6个月两组视力均较治疗前有所提高(P0.05);治疗后1、3、6个月两组渗漏均比治疗前减少(P0.05),治疗后6个月两组间比较,观察组优于PDT组(P0.05)。治疗后1、6个月观察组黄斑中心凹层间厚度均少于对照组(P0.05)。结论中药干预下的PDT可以稳定及增强PDT对CNV的封闭作用,同时抑制新生血管生成,更好地维持和改善患者的视功能,较单纯PDT治疗更有优势。
[Abstract]:Objective to observe the clinical effect of tonifying kidney and invigorating spleen combined with photodynamic therapy (PDT) in the treatment of choroidal neovascularization (CNV). Methods 27 cases (30 eyes) with CNV were divided into two groups, 13 cases (15 eyes) in the control group were treated with PDT alone, and 14 cases (15 eyes) in the observation group were treated with traditional Chinese medicine on the basis of PDT treatment. The visual acuity, leakage and the thickness of macular central concave were observed and compared between the two groups. Results the visual acuity of the two groups was improved at 1, 3 and 6 months after treatment (P 0.05). 1, 3, 6 months after treatment, the leakage of the two groups decreased compared with the pre-treatment group (P0.05), and the observation group was better than the PDT group in the 6 months after treatment (P0.05). At 1 and 6 months after treatment, the thickness of macular concavity in the observation group was less than that in the control group (P 0.05). Conclusion PDT under the intervention of traditional Chinese medicine can stabilize and enhance the blocking effect of PDT on CNV, inhibit neovascularization, maintain and improve the visual function of patients, and has more advantages than PDT alone.
【作者单位】：广东省佛山市中医院眼科;
【基金】：广东省中医药局建设中医药强省立项资助科研课题(编号:20121060)
【分类号】：R774.5

【参考文献】