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颅顶慢反应阈值与纯音测听阈值的比较

发布时间:2019-06-08 11:23
【摘要】: 目的:探索颅顶慢反应(slow vertex response,SVR)在不同频率、不同强度声刺激条件下的变化规律;探讨SVR阈值与纯音测听(pure tone audiometry,PTA)阈值之间的相互关系及其在法医学听力学评估中的应用价值。 方法:对46名听力正常人(92耳)分别进行PTA及SVR测试,标记不同声刺激强度的SVR的N1波、P2波,得出三个分析指标(N1波潜伏期、P2波潜伏期、N1-P2波幅)的数值,分析分析指标随声刺激强度降低的变化规律;测得46名听力正常人(92耳)的SVR阈值及PTA阈值,运用配对t检验对两阈值进行比较,并确定各频率的SVR阈值与PTA阈值差值;对25名感音神经性耳聋患者(40耳)分别进行PTA及SVR测试,根据PTA阈值分成轻度、中度及重度听力障碍组,然后对各组的SVR阈值及PTA阈值比较,并对SVR阈值与PTA阈值进行相关分析,拟出根据受试者SVR阈值推导受试者行为听阈的线性回归方程。 结果:①46名听力正常人均能诱发清晰、稳定的SVR波形。SVR的N1波潜伏期、P2波潜伏期随声刺激强度的降低逐渐延迟,N1-P2波幅随着声刺激强度的降低逐渐降低。②听力正常人各频率的SVR阈值高于PTA阈值,两阈值平均差值约在5dB HL~10dB HL之间。此外,两阈值间的差值随着频率的增高有增大趋势,表明在低频声刺激时SVR阈值更接近于PTA阈值,更能准确反映受试者的低频听力。③在各个检测频率,SVR阈值与PTA阈值均高度相关。不同听力水平受试者0.5kHz时SVR阈值与PTA阈值的r值=0.971(p0.05),一元线性回归方程为Y=-3.582+1.020x;1kHz时SVR阈值与PTA阈值的r值=0.97(6p0.05),一元线性回归方程为Y=-3.869+1.013x;2kHz时SVR阈值与PTA阈值的r值=0.957(p0.05),一元线性回归方程为Y=-6.108+1.011x;4kHz时SVR阈值与PTA阈值的r值=0.928(p0.05),一元线性回归方程为Y=-5.671+1.022x。回代检验结果表明,应用一元线性回归方程评估听力有望成为一个简单可行的方法。 结论:①在适宜的条件下,SVR是一项稳定的测听技术;颅顶慢反应的分析指标随声刺激强度的变化规律在听阈评估具有重要意义。②运用SVR阈值来推断听力正常人行为听阈时,在各检测频率需要对SVR阈值进行校正。③根据建立的应用SVR阈值推断行为听阈的线性回归方程可以较准确的评估受试者的行为听阈。
[Abstract]:Objective: to explore the changes of cranioparietal slow response (slow vertex response,SVR) under different frequencies and intensities of acoustic stimulation. To explore the relationship between SVR threshold and pure tone audiometric (pure tone audiometry,PTA threshold and its application value in forensic audiology evaluation. Methods: 46 normal hearing subjects (92 ears) were tested by PTA and SVR, respectively. The N1 wave and P2 wave of SVR with different acoustic stimulation intensity were marked, and the values of three analytical indexes (N1 wave latency, P2 wave latency, N1-P2 amplitude) were obtained. The variation of indexes with the decrease of acoustic stimulation intensity was analyzed. The SVR threshold and PTA threshold of 46 normal hearing subjects (92 ears) were measured. The two threshold values were compared by pairing t test, and the difference between SVR threshold and PTA threshold of each frequency was determined. 25 patients with sensorineural deafness (40 ears) were tested by PTA and SVR respectively. according to the PTA threshold, they were divided into mild, moderate and severe hearing impairment groups, and then the SVR threshold and PTA threshold of each group were compared. The correlation between SVR threshold and PTA threshold was analyzed, and the linear regression equation of behavioral hearing threshold was deduced according to the SVR threshold of the subjects. Results: 146 normal hearing subjects could induce clear and stable SVR waveforms. The N1 wave latency and P2 wave latency of SVR were gradually delayed with the decrease of acoustic stimulation intensity. The amplitude of N1-P2 decreased gradually with the decrease of acoustic stimulation intensity. 2 the SVR threshold of each frequency in normal hearing subjects was higher than the PTA threshold, and the average difference between the two threshold values was about between 5dB HL~10dB HL. In addition, the difference between the two threshold values tends to increase with the increase of frequency, which indicates that the SVR threshold is closer to the PTA threshold during low frequency acoustic stimulation, and can more accurately reflect the low frequency hearing of the subjects. 3 at each detection frequency, The SVR threshold is highly correlated with the PTA threshold. The r value of SVR threshold and PTA threshold was 0.971 (p0.05), and the univariate linear regression equation was Y 鈮,

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