3种不同他汀类药物治疗高脂血症的成本-效果分析

发布时间：2018-01-18 15:14

本文关键词：3种不同他汀类药物治疗高脂血症的成本-效果分析　出处：《中国药房》2015年26期 　论文类型：期刊论文

【摘要】：目的:比较3种不同他汀类药物治疗高脂血症的成本-效果。方法:将180例高脂血症患者按随机数字表法分为3组,各60例。A组患者服用阿托伐他汀钙片20 mg/次,1次/d;B组患者服用辛伐他汀片20 mg/次,1次/d;C组患者服用瑞舒伐他汀钙片10 mg/次,1次/d。疗程均为8周。评价3组患者治疗效果,并进行成本-效果分析。结果:A、B、C组患者的有效率分别为85.0%、83.3%、81.7%,组间比较差异无统计学意义(P0.05)。A、B、C组治疗总费用分别为610.40、193.60元、408.00元;B组的成本-效果比为2.32,显著低于A组的7.18与C组的4.99,组间比较差异具有统计学意义(P0.05)。敏感度分析具有同样的研究结果。结论:辛伐他汀为治疗高脂血症较为有效、经济的药物。
[Abstract]:Objective: To compare the effect of 3 kinds of statins in the treatment of hyperlipidemia cost. Methods: 180 patients with hyperlipidemia were randomly divided into 3 groups, 60 cases in each.A group of patients taking the Atorvastatin Calcium Tablets 20 mg/ time, 1 times /d; B group of patients taking the Simvastatin Tablets 20 mg/ times, 1 times /d; C group of patients taking the Rosuvastatin Calcium Tablets 10 mg/ time, 1 times /d. for 8 weeks. The treatment effect was evaluated in 3 groups, and the cost-effectiveness analysis. Results: A, B, C group of patients with effective rate were 85%, 83.3%, 81.7%, there was no significant difference between groups (P0.05).A, B, C group total cost for 610.40193.60 yuan, 408 yuan; B group cost-effectiveness ratio was 2.32, significantly lower than the 4.99 A group and 7.18 C group, the difference was statistically significant (P0.05). Results with the same sensitivity analysis. Conclusion: simvastatin for the treatment of hyperlipidemia Effective, economic drugs.

【作者单位】：江苏盛泽医院药剂科;
【分类号】：R95
【正文快照】： *副主任药师。研究方向:临床药学、药事管理。电话:0512-63097281。E-mail:wjbairong@163.com高脂血症,如动脉粥样硬化、冠心病、胰腺炎等,是常见的心血管疾病,严重危害人体健康。该病症在我国中老年人群中较为多见,常由于代谢性紊乱疾病如糖尿病、高血压、甲状腺功能低下、肥

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