基于近邻传播聚类分析的医生处方数据研究

发布时间：2018-01-18 23:52

本文关键词： 处方行为数据仓库近邻传播聚类抗生素统计分析　出处：《浙江工业大学》2014年硕士论文　论文类型：学位论文

【摘要】：本文利用世界卫生组织(WHO)提出的适合不同国家及地区的药物基本处方指标,反映了浙江省某地区基本药物制度实施效果,利用2009年与2012年浙江省某医院的处方数据,分析国家实施基本药物制度前后该医院的用药水平,同时确定研究建立医院处方数据仓库所需要的对象,从医生维度、患者维度、药品维度、时间维度四方面对处方用药现状进行分析,在进一步探讨抗生素处方用药方面,对抗生素相关数据使用MATLAB软件及近邻传播聚类算法进行聚类分析,得出具有代表性医生数据的训练集和测试集,并利用SAS9.1对其进行方差分析、配对非参数检验,分析医生处方行为的影响因素及其评价指标,最后利用logistic回归方法对找到的影响因素进一步分析,验证实验结果。结果表明,国家实施基本药物制度前后,处方总体指标与抗菌药物指标均无显著性差异,并且在具体抗生素处方方面,不同科室、不同月份、不同抗生素种类、医生的年龄、级别、性别以及药品公司对医生的抗生素处方数据有显著影响,总抗生素处方数量随季节变化和喹诺酮类药物处方数量随季节变化无显著性差异,青霉素、头孢菌素处方数量随季节变化有显著性差异,可作为医生的处方评价指标。通过本文的研究方法能够找出最具代表性医生的处方数据,进而分析得出医生抗生素处方行为的影响因素以及医生抗生素处方行为的评价指标,根据处方数据分析结果讨论给出建议措施,医院可以对影响因素及其评价指标合理干涉控制,能从一定程度上规范医生的处方行为。
[Abstract]:In this paper, the basic prescription index for different countries and regions was proposed by World Health Organization (WHO) to reflect the implementation effect of essential drug system in a certain area of Zhejiang Province. Based on the prescription data of a hospital in Zhejiang province on 2009 and 2012, the level of drug use in a hospital before and after the implementation of the national essential drug system was analyzed. At the same time, to determine the research needs of the establishment of hospital prescription data warehouse, from the doctor dimension, patient dimension, drug dimension, time dimension to analyze the current situation of prescription drug use. In the further study of antibiotic prescription drug use, the antibiotic related data is analyzed by MATLAB software and neighbor propagation clustering algorithm, and the training set and test set of representative doctor data are obtained. SAS9.1 was used to carry out variance analysis, paired non-parametric test, and to analyze the influencing factors and evaluation indexes of doctors' prescription behavior. Finally, the logistic regression method was used to further analyze the influencing factors, and verify the experimental results. The results show that the country before and after the implementation of the basic drug system. There was no significant difference between the general prescription index and the antimicrobial index, and in the specific antibiotic prescription, different departments, different months, different types of antibiotics, the age of the doctor, grade. Sex and drug companies had significant influence on the prescription data of antibiotics. There was no significant difference in total antibiotic prescriptions with seasons and quinolones prescriptions with seasons, penicillin. The number of cephalosporin prescriptions varies significantly with the season, and can be used as a prescription evaluation index for doctors. The most representative prescription data of doctors can be found by the research method in this paper. Then, the influencing factors of the prescription behavior of antibiotics and the evaluation index of the prescription behavior of the doctors are analyzed, and the suggestions are given according to the analysis results of the prescription data. Hospitals can reasonably interfere with the influencing factors and their evaluation indexes, and regulate the prescription behavior of doctors to a certain extent.
【学位授予单位】：浙江工业大学
【学位级别】：硕士
【学位授予年份】：2014
【分类号】：R95

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