注射用盐酸氨溴索的临床应用现状与思考

发布时间：2018-02-23 21:21

本文关键词： 注射用盐酸氨溴索临床应用合理用药　出处：《中国药学杂志》2015年09期 　论文类型：期刊论文

【摘要】：目的评价注射用盐酸氨溴索的临床应用现状,促进安全合理用药。方法以《医院处方分析合作项目》为基础,随机抽取北京、上海、广州、杭州、成都、天津6个城市82家综合医院2010年~2013年160 d的注射用盐酸氨溴索处方数据,参考药品说明书、相关指南、专家共识及文献资料,对该药品的临床使用情况进行调查与分析。结果在抽样时间范围内,6个城市中该药品的处方总量共计267.49万张,药品总用量共计1 400.64万支(以每支15 mg计);各城市按照说明书用药的处方百分率由高到低排序依次为杭州(28.03%)成都(26.25%)上海(14.66%)广州(9.38%)北京(7.72%)天津(3.98%);然而该药品在给药途径、用法用量、适应证方面均存在不同程度的说明书外过度使用现象。结论目前临床上以说明书外用法用量使用注射用盐酸氨溴索的现象较为普遍,应予以规范。
[Abstract]:Objective to evaluate the clinical application of ambroxol hydrochloride for injection and to promote the safe and rational use of ambroxol. Methods based on the Hospital prescription Analysis Project, Beijing, Shanghai, Guangzhou, Hangzhou and Chengdu were randomly selected. The prescription data of ambroxol hydrochloride for injection in 82 general hospitals in 6 cities of Tianjin from 2010 to 2013 were reviewed with reference to drug instructions, related guidelines, expert consensus and literature materials. The clinical use of the drug was investigated and analyzed. Results the total number of prescriptions in 6 cities was two million six hundred and seventy-four thousand and nine hundred . The total dosage of the drugs was fourteen million six thousand and four hundred (in the order of 15 mg per drug; the prescription percentage of the prescriptions in the cities according to the instructions was Hangzhou 28. 03) Chengdu was 26.25.) Shanghai was 14. 66) Guangzhou was 9. 38) Beijing was 7. 72) and Tianjin was 3.98; however, the drug was administered in the way it was administered. The usage and indication of ambroxol hydrochloride for injection are common in clinical practice and should be standardized.
【作者单位】：中国医学科学院北京协和医学院北京协和医院药剂科;
【分类号】：R969.3

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