我中心2011-2014年抗艾滋病毒药物应用分析

发布时间：2018-02-23 22:06

本文关键词： 抗艾滋病毒药物销售金额用药频度日均费用职业暴露　出处：《中国药房》2017年17期 　论文类型：期刊论文

【摘要】：目的:为临床合理使用及管理抗艾滋病毒药物提供参考,并为职业暴露制订免费用药政策提供依据。方法:采用回顾性研究方法,按照世界卫生组织推荐的限定日剂量(DDD)法进行计算,对我中心2011-2014年使用抗艾滋病毒药物的销售金额、用药频度(DDDs)、日均费用(DDC)和序号比(B/A)等进行分析和评价。结果:我中心2011-2014年抗艾滋病毒药物销售金额呈先升高后降低的趋势,由2011年的512 112元上升至2012年的650 854元,然后逐年降低至2014年的496 473元;DDDs由2011年的35 932逐年下降至2014年的16 363。核苷酸类逆转录酶抑制剂的销售金额在2012-2014均列第1位,DDDs在2011、2013、2014年均列第1位。齐多夫定片的DDDs在2013、2014年列第1位,唐草片的DDDs在2011-2014年均列前3位。富马酸替诺福韦二吡呋酯片、齐多拉米双夫定片、恩曲他滨替诺福韦片、洛匹那韦利托那韦片的DDC较高,在46元以上;齐多夫定片、司他夫定片、奈韦拉平片的DDC较低,在6元以下。富马酸替诺福韦二吡呋酯片、司他夫定片和依非韦伦片的B/A值4年均在0.5~1.5,唐草片在2013、2014年的B/A=1,社会效益和经济效益同步性较好。结论:我中心抗艾滋病毒药物临床使用基本合理,药物应用与职业暴露预防用药基本相符,中药制剂的应用符合临床用药需求。
[Abstract]:Objective: to provide a reference for the rational use and management of anti-HIV drugs in clinic and to provide the basis for the establishment of free drug use policy for occupational exposure. In accordance with the limited daily dose DDD method recommended by the World Health Organization, the amount of sales of anti-HIV drugs used by our center in 2011-2014 was calculated. The frequency of drug use was analyzed and evaluated by DDDsN, daily average cost (DDC) and serial number (B / A). Results: the sales amount of anti-HIV drugs in our center increased first and then decreased from 512,112 yuan on 2011 to 650,854 yuan on 2012, the results showed that the sales amount of anti-HIV drugs in our center increased first and then decreased from 512,112 yuan on 2011 to 650,854 yuan on 2012. In 2014, the DDDs decreased from 35932 on 2011 to 16363.The sales amount of nucleotide reverse transcriptase inhibitors ranked first in 2012-2014 in 2011 / 2011, and in 2014 in 1st place. DDDs of zidovudine tablets was ranked first. In 2013, in 2014, No. 1, The DDDs of Tangcao tablets was in the top 3 in 2011-2014. The DDC of tenofovir Fumarate dipyrifuroxime tablets, zidolamitine difurofovir tablets, entrotropine tenofovir tablets and Lopinowilitonavir tablets were higher than 46 yuan. The DDC of stavudine tablets was lower than that of nevirapine tablets, which was below $6. Tenofovir dipyrifuroxime fumarate tablets, The average value of B / A of Stavudine tablets and Efeveron tablets was 0.5 ~ 1.5 a year, and B / A of Tangcao tablets in 2003 and 2014 was better. Conclusion: the clinical use of anti-HIV drugs in our center is basically reasonable. The drug use is basically consistent with the occupational exposure prevention medication, and the application of traditional Chinese medicine is in line with the clinical needs.
【作者单位】：重庆市公共卫生医疗救治中心药剂科;
【分类号】：R978.7

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