药学干预对临床合理应用抗生素的影响以及相关价值

发布时间：2018-02-24 04:37

本文关键词： 药学干预抗生素合理使用住院费用　出处：《当代医学》2016年35期 　论文类型：期刊论文

【摘要】：目的探讨药学干预对临床合理应用抗生素的影响。方法为促进抗生素的合理使用,大连市第二人民医院于2014年7~12月开展临床药师药学干预,随机抽取呼吸内科168例患者的临床资料进行分析,并与2014年1~6月(干预前)168例临床资料进行比较研究,观察抗生素不合理使用改善情况,比较2组患者治疗效果及住院费用。结果干预后抗生素未按PD/PK 2给药、联合用药不合理、剂量过大、换药过频等不合理使用率15.48%明显低于干预前25.60%(χ~2=5.271,P0.05);平均住院时间短于干预前,住院费用明显少于干预前(t=7.822,19.296,P0.05)。结论临床药师药学干预可促进抗生素的合理使用,提高治疗效果,降低患者的经济负担,促进患者康复,因此值得在临床上大力推广应用。
[Abstract]:Objective to explore the effect of pharmaceutical intervention on rational clinical use of antibiotics. Methods in order to promote the rational use of antibiotics, the second people's Hospital of Dalian carried out pharmacists' intervention from 2014 to December. The clinical data of 168 patients in Department of Respiratory Medicine were randomly selected for analysis and compared with 168 cases of clinical data from 2014 to June (before intervention) to observe the improvment of irrational use of antibiotics. Results after intervention, antibiotics were not given according to PD/PK _ 2, the combined use of antibiotics was unreasonable, the dosage was too large, and the irrational utilization rate of changing medicine too frequently was significantly lower than that before intervention (蠂 ~ (2 +) 25.271) (P 0.05), and the average hospital stay was shorter than that before intervention. Conclusion Pharmacological intervention by clinical pharmacists can promote the rational use of antibiotics, improve the effect of treatment, reduce the economic burden of patients, and promote the rehabilitation of patients, so it is worth popularizing and applying in clinic.
【作者单位】：大连市第二人民医院药剂科;
【分类号】：R95

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