患者参与药物临床试验影响因素的分析与评价

发布时间：2018-02-27 17:32

本文关键词： 临床试验患者态度相关因素　出处：《中国全科医学》2016年03期 　论文类型：期刊论文

【摘要】：本文以"药物临床试验""患者""态度""意愿""参与度"为检索词,检索了中国生物医学文献数据库、中文科技期刊数据库、相关期刊论文、万方数据库、EBSCO、Pub Med、OVID、Web of Science从建库到2015年4月的文献6 804篇,最终纳入38篇。对文献进行阅读和资料提取后,定性分析和总结纳入文献的相关信息。发现影响患者参与药物临床试验的因素包括4个维度15个具体要素,并发现国外关于影响患者参与药物临床试验态度的研究数量、研究对象多于国内,但由于研究工具和样本大小的差异,部分影响因素存在分歧,故有待高质量的横纵向研究加以验证。
[Abstract]:In this paper, the Chinese Biomedical Literature Database, the Chinese Sci-tech Journal Database, the Chinese Journal Full-text Database, and the Chinese Journal Full-text Database were searched with the keywords of "patient's attitude," "patient's attitude," "willingness" and "participation degree". There are 6 804 documents from the establishment of the database to April 2015, and 38 articles are included in the database. After reading and extracting the literature, Qualitative analysis and summary of relevant information included in the literature. It was found that the factors influencing patients' participation in drug clinical trials included 4 dimensions and 15 specific factors, and found that the number of foreign studies affecting patients' attitude to drug clinical trials. The number of subjects is more than domestic, but due to the difference of research tools and sample size, some influencing factors are different, so it needs to be verified by high quality horizontal and longitudinal research.
【作者单位】：重庆医科大学公共卫生与管理学院医学与社会发展研究中心健康领域社会风险预测治理协同创新中心;重庆医科大学附属儿童医院科研处;重庆医科大学附属儿童医院药剂科;重庆医科大学附属儿童医院医保办;
【基金】：重庆市卫生与计划生育委员会项目(20142045)
【分类号】：R969.4

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