266例儿童药品不良反应报告分析

发布时间：2018-03-21 23:42

本文选题：药品不良反应　切入点：儿童　出处：《中国医院用药评价与分析》2016年01期 　论文类型：期刊论文

【摘要】：目的:了解广西壮族自治区玉林市妇幼保健院(以下简称"我院")儿童药品不良反应(adverse drug reaction,ADR)发生的基本情况、相关因素及特点,为促进该地区ADR监测及儿童安全用药提供参考。方法:对2012—2014年我院筛选出的266例儿童ADR报告,进行性别及年龄、给药途径、给药时间、药物类别、所累及器官和(或)系统和临床表现、转归、ADR报告情况进行统计分析。结果:266例ADR报告中,0~3岁发生较多,共188例(占70.68%);由静脉滴注引起的有246例(占92.48%);用药过程中0~30 min出现较多,有219例(占82.33%);中成药注射剂117例(占43.98%)和抗菌药物105例(占39.47%)所致ADR最常见;累及皮肤及其附件损害的有209例(占73.33%);报告情况中严重的5例(占1.88%),其中1例(占0.38%)为新的严重的ADR;其余为一般的,其中7例(2.68%)为新的一般的ADR。结论:医院管理及临床治疗应更重视儿童ADR的发生,促进临床合理用药、安全用药。
[Abstract]:Objective: to understand the basic situation, related factors and characteristics of adverse drug reaction (ADR) in children in Yulin Maternal and Child Health Care Hospital of Guangxi Zhuang Autonomous region (hereinafter referred to as "our hospital"). Methods: a total of 266 children with ADR, selected from our hospital from 2012 to 2014, were reported with sex and age, route of administration, time of administration, drug type, and so on, in order to promote the monitoring of ADR in this area and the safe use of drugs in children. The clinical manifestations and organs involved were statistically analyzed. Results there were more cases of ADR in the age of 3 years in 2. 266 cases of ADR. There were 188 cases (70.68%), 246 cases (92.48%) were caused by intravenous drip, 219 cases (82.33%) appeared during 30 min, 117 cases (43.98%) and 105 cases (39.47%) of ADR caused by Chinese patent medicine injection and antimicrobial agent 105 cases. 209 cases (73.33%) were involved in skin and its adnexal lesions; 5 cases (1.88%) were severe in the reported situation, of which 1 case (0.38%) was a new serious ADR; the rest were general. Conclusion: hospital management and clinical treatment should pay more attention to the occurrence of ADR in children and promote rational drug use and safe drug use.
【作者单位】：玉林市妇幼保健院药剂科;
【分类号】：R95

【相似文献】