抗菌药物在专项整治过程中清洁手术预防使用抗菌药物的调查

发布时间：2018-04-14 14:20

本文选题：清洁手术 + 专项整治　；参考：《中华医院感染学杂志》2017年05期

【摘要】：目的了解医院在抗菌药物专项整治活动后的合理使用的情况及持续效果,为医院规范围术期预防使用抗菌药物及建立有效的干预措施提供参考。方法调查医院2016年1-7月全院清洁手术出院病历1 432份,对清洁手术预防性使用抗菌药物的使用率、用药品种选择规范率、抗菌药物使用频率与类别、术前给药时机符合率及预防用药总时间进行评价。结果 2016年1-7月某院妇产科、肝胆外科、骨科二病区、骨科一病区、普外科、乳腺外科、泌尿外科及脑外科清洁手术抗菌药物预防使用率分别为58.46%、16.22%、49.47%、55.90%、7.94%、16.22%、73.33%及76.47%,预防用药品种规范率分别为97.37%、72.22%、74.19%、75.93%、90.00%、91.67%、72.73%及96.15%,全院清洁手术抗菌药物预防使用率为41.55%,预防用药品种规范率为78.66%;2016年1-7月某院抗菌药物使用频率较高的为头孢菌素类,其中排名前三的为头孢呋辛占34.62%、头孢硫脒占33.45%及头孢他啶占18.66%,分别属于第二代、第一代与第三代头孢菌素;全院清洁手术术前给药时机在0.5-1h占总数的88.57%,其中24h停药率为14.12%,48h停药率为25.38%。结论清洁手术预防使用抗菌药物的给药时机情况较好,抗菌药物的使用率、品种的选择及使用疗程都存在一定的不合理性。
[Abstract]:Objective to understand the rational use of antimicrobial drugs in hospitals after special treatment activities and to provide references for the prevention and use of antimicrobial agents and the establishment of effective intervention measures during the period of hospital regulation.Methods A total of 1 432 medical records of clean surgery were collected from January to July 2016 in our hospital. The usage rate of prophylactic use of antimicrobial agents, the standard rate of drug choice, the frequency and category of use of antimicrobial agents in clean surgery were investigated.The coincident rate of preoperative administration and the total time of prophylactic medication were evaluated.Results from January to July 2016, a hospital, including gynecology and obstetrics, hepatobiliary surgery, orthopedic department, orthopedic department, general surgery, breast surgery,The rate of prophylactic use of antimicrobial agents in urological surgery and brain surgery cleaning surgery was 58.460.16.22% and 16.223.33% and 76.47%, respectively. The standard rate of prophylactic drugs was 97.377.37 and 72.222.19, respectively, which was 91.6772.73% and 96.15153.73%, 41.5555, 78.66%, 78.66%, respectively.Cephalosporins were the most frequently used antimicrobial agents in a hospital from January to July.The top three were cefuroxime in 34.62%, cefathiramidine in 33.45% and ceftazidime in 18.66, belonging to the second generation, the first generation and the third generation of cephalosporins, respectively.The time of administration before cleaning operation in the whole hospital was 88.57% in 0.5-1 h, and the stopping rate in 24 h was 14.12% and 25.38% in 48h.Conclusion the timing of prophylactic use of antimicrobial agents in clean surgery is better, and the utilization rate of antibiotics, the selection of varieties and the course of treatment are all irrationality.
【作者单位】：南通市第三人民医院药学部;
【基金】：南通市临床医学中心项目(HS2016002)
【分类号】：R978.1

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