缓控释技术在药物防治心血管疾病中的应用

发布时间：2018-05-04 11:05

本文选题：心血管疾病 + 口服缓控释制剂　；参考：《中国医院药学杂志》2017年11期

【摘要】：缓控释药物在心血管疾病的治疗中起效平稳、释药时间长,具有良好的开发应用前景。本文对近年来国内外心血管疾病的口服缓控释制剂的研究现状进行综述,概述了渗透泵型、骨架型、脉冲型、包衣型、微丸、胶囊及微囊制剂的研究进展,为研发防治心血管疾病的缓控释药物提供参考,对更好地满足患者的用药需求具有积极意义。同时也对心血管缓控释制剂的发展进行了展望。
[Abstract]:Slow and controlled release drugs have a good prospect of development and application because of their stable effect and long release time in the treatment of cardiovascular diseases. In this paper, the research status of oral controlled release preparations for cardiovascular diseases at home and abroad was reviewed, and the research progress of osmotic pump type, skeleton type, pulse type, coating type, pellet, capsule and microcapsule preparation were summarized. To provide a reference for the research and development of controlled release drugs for the prevention and treatment of cardiovascular disease, to better meet the needs of patients with drug use has a positive significance. At the same time, the development of cardiovascular controlled release preparations is also prospected.
【作者单位】：哈尔滨商业大学药学院;
【基金】：黑龙江省应用技术研究与开发计划项目(编号:GC13C106) 黑龙江省教育厅科学技术研究项目(编号:12541198) 哈尔滨商业大学研究团队支持项目(编号:2016TD009)
【分类号】：R943

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