某院替加环素药物利用评价标准的建立与应用分析

发布时间：2018-05-09 03:02

本文选题：替加环素 + 合理用药　；参考：《中国药房》2017年14期

【摘要】：目的:建立替加环素药物利用评价(DUE)标准,为临床合理使用替加环素提供参考。方法:以替加环素药品说明书为基础,参照相关规范和文献,建立替加环素DUE标准;并以此为依据,采用回顾性研究方法,对某院2012年11月-2016年10月179例住院患者替加环素使用的管理指标、用药指征、用药过程、用药结果等进行综合评价分析。结果:该院替加环素DUE标准评价结果显示,病历中有会诊记录的患者比例为83.2%(目标值为100%),微生物送检率为90.5%(目标值为80%);用药指征符合标准百分率为98.9%(目标值为90%);溶剂选择、给药途径、药物相互作用、配伍禁忌、特殊人群用药符合标准百分率为100%(目标值为100%);处方权限符合标准百分率为20.1%(目标值为100%);给药剂量和给药间隔符合标准百分率为7.3%(目标值为100%);有效率为54.7%(目标值为80%)。结论:本研究所建立的替加环素DUE标准可用于规范替加环素的临床使用。
[Abstract]:Objective: to establish a standard for evaluation of tegacycline drug use and to provide reference for rational clinical use of tegacycline. Methods: the DUE standard of tegacycline was established on the basis of the specification of tegacycline, referring to the relevant norms and literature, and the method of retrospective study was used. From November 2012 to October 2016, the management indexes, indications, course and results of tegacyclin use in 179 inpatients in a hospital were evaluated and analyzed. Results: the results of the DUE standard evaluation of tegacycline showed that the proportion of patients with consultation records was 83.2 (the target value was 100m, the microbial examination rate was 90.5) (the target value was 80), the percentage of conformity of drug indications was 98.9 (target value was 90), solvent selection, Drug delivery route, drug interaction, compatibility taboo, The standard percentage of drug administration in special population was 100 (target value 100); the standard percentage of prescription authority was 20.1; the target value was 100; the dosage and interval of administration were 7.3%; the target value was 100; the effective rate was 54.7 (target value was 80). Conclusion: the tegacycline DUE standard established in this study can be used to standardize the clinical use of tegacycline.
【作者单位】：中山市人民医院药学部;中山市人民医院呼吸内科;中山市人民医院血液内科;
【基金】：中山市科技计划项目(No.2015B1117)
【分类号】：R978.1

【相似文献】