Ⅰ类切口手术预防性用药的药学干预与意义探析

发布时间：2018-05-23 12:14

本文选题：I类切手术 + 抗菌药物　；参考：《世界最新医学信息文摘》2016年A2期

【摘要】：目的对比分析Ⅰ类切口手术预防性用药进行药学干预的临床意义。方法选取我院2015年至2016年Ⅰ类切口手术病理300份,分为对照组和观察组,每组患者150例,对照组为未开展药学干预之前手术患者病例,观察组为开展药学干预之后手术患者病例。设计《手术患者抗菌药物情况调查表》内容包括:姓名、年龄、出院日期、诊断、手术名称、手术日期、抗菌药物预防使用情况。围手术期预防用药参考《抗菌药临床指导原则》相关规定,从预防用药的用药率、分级等指标在用药干预前后进行对比。结果非干预组Ⅰ类切口围手术期非限制使用级使用频次为28例,干预组为20例;肺干预组Ⅰ类切口围手术期限制使用级抗菌药物频次为104例,干预组为13例。非干预组使用的抗菌药物品种有5个品种,干预组为4个品种,在非干预组中,使用频次最高的3种抗菌药物分别为头孢硫脒、头孢替安、头孢拉啶;在进行药学干预后,使用频次最高的3种抗菌药物分别为头孢呋辛钠、头孢曲松钠、头孢硫脒,头孢硫脒的使用频次非干预组为34次,干预组为6次,两组差异统计学显著(P0.05)。结论在Ⅰ类切口手术预防用药中开展药学干预可使临床用药更加规范合理、经济高效。
[Abstract]:Objective to compare and analyze the clinical significance of pharmaceutical intervention with prophylactic medication in type I incision surgery. Methods from 2015 to 2016, 300 patients with type I incision in our hospital were divided into control group and observation group with 150 patients in each group. The patients in the observation group were operated after pharmacological intervention. The contents of the questionnaire include: name, age, discharge date, diagnosis, operation name, operation date, antibiotic prophylaxis. In the perioperative period, the preventive use of drugs referred to the clinical guidelines of antimicrobial drugs, from the preventive drug use rate, grading and other indicators before and after intervention were compared. Results there were 28 cases in the non-intervention group and 20 cases in the intervention group during the perioperative period, and 104 cases in the lung intervention group and 13 cases in the intervention group. There were 5 varieties of antimicrobial agents used in the non-intervention group and 4 varieties in the intervention group. In the non-intervention group, the three most frequently used antimicrobial agents were cefathiamidine, ceftidine and cefradine, respectively; after pharmacological intervention, the three antimicrobial agents were cefathiramidine, ceftidine and cefradine respectively. The three most frequently used antibiotics were cefuroxime sodium, ceftriaxone sodium and cefathiramidine for 34 times in the non-intervention group and 6 times in the intervention group. The difference between the two groups was statistically significant (P 0.05). Conclusion Pharmacological intervention can make clinical medication more rational, economical and efficient.
【作者单位】：连云港市第一人民医院药学部;
【分类号】：R95

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