阿奇霉素研究进展

发布时间：2018-06-09 01:05

本文选题：阿奇霉素 + 药理作用　；参考：《泰山医学院学报》2016年11期

【摘要】：正阿奇霉素(azithromycin,AZM)是一种新型大环内酯类抗生素,它是由红霉素A9-酮基肟后经Beckman重排,N-甲基化等一系列反应所得。1980年被克罗地亚Pliva公司研制,并在世界范围内上市,至今已应用30余年。阿奇霉素为结晶性粉末状,易溶于无水乙醇、丙酮、稀盐酸、甲醇等,一般为类白色或白色,味苦,无臭~([1])。阿奇霉素作为第2代大环内酯类抗生素,其抗菌谱与红霉素相仿,具有抗菌谱广的
[Abstract]:Azithromycin (AZM) is a new macrolide antibiotic derived from a series of reactions, such as erythromycin A9-ketoxime, Beckman rearrangement of N-methylation, and so on. It was developed by Croatian company Pliva in 1980 and listed worldwide. It has been used for more than 30 years. Azithromycin is crystalline powder, easily soluble in anhydrous ethanol, acetone, dilute hydrochloric acid, methanol, etc. Azithromycin as the second generation macrolides antibiotics, its antibacterial spectrum is similar to erythromycin, has a wide antibacterial spectrum.
【作者单位】：泰山医学院药学院;
【基金】：山东省科技发展计划(2013YD18018)
【分类号】：R978.1

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