8760例住院患者人血白蛋白临床使用分析与评价

发布时间：2018-06-20 00:53

本文选题：人血白蛋白 + 临床应用　；参考：《中国药房》2017年08期

【摘要】：目的:为人血白蛋白临床合理使用提供参考。方法:回顾性调查我院2014年1-12月使用人血白蛋白的住院患者病例,统计患者一般资料、用药前血清白蛋白水平、用药量、费用、用药原因等信息,并进行分析。结果:人血白蛋白使用人数最多的8个科室共8 760例患者纳入研究,占全院使用人血白蛋白住院患者的64%。其中,男性5 244例(占59.9%),女性3 516例(占40.1%),患者年龄主要集中在30~60岁(占52.6%)。白蛋白使用人数最多的科室为普通外科(2 588例)和心血管外科(2 348例)。以国内说明书作为参照标准时,该院有8 210例(约93.7%)患者符合适应证,低蛋白血症为最常见的用药指征(占35.6%)。重症监护治疗病房人均使用量最高(152.5 g),普通外科总用药金额最高(13 334 396.4元),传染科人均使用疗程最长(10.7 d)。结论:我院存在人血白蛋白不合理使用情况,科室间使用情况存在差异。应加强对人血白蛋白使用的监督,建立合理的用药评估体系,以促进用药规范,实现医疗资源合理分配。
[Abstract]:Objective: to provide reference for the rational use of human serum albumin (HSA). Methods: the data of patients with human serum albumin (HSA) in our hospital from January to December 2014 were retrospectively investigated and analyzed. Results: 8 760 patients were included in the study in 8 departments, which accounted for 64% of the inpatients who used human serum albumin (HSA) in the whole hospital. There were 5 244 males (59.9%) and 3 516 females (40.1%). The age of the patients was mainly 30 ~ 60 years old (52.6%). The most common use of albumin was in general surgery (2 588 cases) and cardiovascular surgery (2 348 cases). When the domestic specification was taken as the reference standard, there were 8 210 patients (93. 7%) in this hospital. Hypoproteinemia was the most common indication of drug use (35. 6%). The per capita usage in intensive care unit was 152.5 g / g, the total sum of total drug used in general surgery was 13 334 396.4 yuan, and the longest course of treatment was 10.7 d in infectious department. Conclusion: unreasonable use of human serum albumin exists in our hospital, and there is difference between departments. The supervision of the use of human serum albumin (HSA) and the establishment of a rational drug use evaluation system should be strengthened in order to promote the standardization of drug use and realize the rational distribution of medical resources.
【作者单位】：中南大学湘雅二医院药学部;中南大学临床药学研究所;阿尔伯塔大学医学与牙科学院/家庭医学部;
【基金】：湖南省药学会生物专项基金资助项目(No.xy2015008)
【分类号】：R977

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