老年患者多重用药调查及共病管理的临床策略

发布时间：2018-06-21 15:39

本文选题：老年患者 + 多重用药　；参考：《中国卫生事业管理》2015年09期

【摘要】：目的:了解老年住院患者多重用药状况,使临床医生对老年患者多重用药的认识更深入,为改善老年人的不合理用药问题及减少由此导致的药物相关不良事件探索新思路。方法:采用随机抽样的方法选取老年科住院患者388例的口服药物长期医嘱单,统计患者的基本情况、疾病诊断、口服药物服用种类、数量及药物不良反应(ADR)。结果:老年住院患者服用5种及其以上药物者占81.4%。日服药种类≥10种的患者ADR发生率高达47.6%,服药数量≥30粒的ADR发生率高达82.8%,服药品种及数量与药物不良反应呈正相关,诊断数目与服药品种及数量呈正相关。结论:多重用药广泛存在于老年患者中,老年患者多重用药易出现药物不良反应,医护人员、患者及家属应提高对多重用药的认识,针对老年患者的共病制定个体化、合理的治疗策略,减少药物不良反应,改善其功能状态和生活质量。
[Abstract]:Objective: to understand the situation of multidrug use in elderly inpatients, to make clinicians know more about multidrug use of elderly patients, and to explore a new way to improve irrational drug use in the elderly and to reduce the adverse events related to drugs. Methods: 388 inpatients in geriatrics were selected by random sampling. The basic condition of the patients, the diagnosis of diseases, the kinds, quantity and adverse reactions of oral drugs were counted. Results: 81.4% of senile inpatients took 5 or more drugs. The incidence of ADR was as high as 47.6 for patients with more than 10 kinds of daily medication and 82.8 for the patients with dosage of more than 30 pills. There was a positive correlation between the variety and quantity of medication and adverse drug reactions, and between the number of diagnoses and the variety and quantity of drugs. Conclusion: multidrug is widely used in the elderly patients, and it is easy to produce adverse drug reactions in the elderly patients. Medical staff, patients and their families should improve their understanding of multiple drug use and make individualization for the common diseases of the elderly patients. Rational treatment strategies to reduce adverse drug reactions and improve their functional status and quality of life.
【作者单位】：四川省医学科学院·四川省人民医院干部医疗科;
【基金】：四川省科技厅科技支撑项目“血清小肠脂肪酸结合蛋白(I-FABP)联合血清瓜氨酸测定在危重症患者胃肠功能衰竭诊治中的临床意义及应用”(编号:2015SZ0164)
【分类号】：R95

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