枳壳终端市场的质量现状调查

发布时间：2018-07-07 21:48

本文选题：市场调查 + 枳壳　；参考：《中国药房》2015年16期

【摘要】：目的:掌握市场上枳壳的销售、流通和质量情况,为制订新的枳壳质量标准及规范枳壳市场秩序提供参考。方法:运用实地抽样调查的方法,对浙江省内的零售药店及医疗机构的药房进行枳壳的专项检查,按照《中国药典》(2010年版)标准,从性状、薄层色谱法(TLC)鉴别和高效液相色谱法(HPLC)含量测定等角度进行分析,并记录药材的原产地及品种来源。结果:在抽查的40批枳壳样品中,有7批性状检查不合格,占总抽样数的17.50%;15批TLC鉴别不合格,占37.50%;15批HPLC含量测定不合格,占37.50%;TLC鉴别与HPLC含量测定存在相关性。40批样品中有32批来源符合《中国药典》规定,1批来源于地方习用品种常山胡柚,另外7批来源于橘类。40批枳壳样品中有16批产自江西、10批产自浙江、12批产自安徽、1批产自湖南,这4个产地均是枳壳的主产地;还有1批产自湖北。结论:枳壳药材中所含的成分受品种、产地、采收时间等影响。目前,枳壳终端市场上枳壳品种混乱、质量参差不齐,市售枳壳的监管力度有待加强,以保障消费者的用药安全、有效。
[Abstract]:Objective: to understand the sale, circulation and quality of Fructus Aurantii on the market, and to provide a reference for establishing a new quality standard of Fructus Aurantii and standardizing the market order of Fructus Aurantii. Methods: the special inspection of Fructus Aurantii was carried out in the pharmacies of retail pharmacies and medical institutions in Zhejiang province, according to the standard of the Chinese Pharmacopoeia (2010 edition), according to the standard of "Chinese Pharmacopoeia" (2010 edition). TLC identification and HPLC analysis were carried out, and the origin and origin of medicinal materials were recorded. Results: of the 40 batches of Fructus Aurantii samples, 7 batches were unqualified, and 17.50 batches of TLC were not qualified, and 37.50 batches of TLC were not qualified for determination of content of Fructus Aurantii. There was a correlation between TLC identification and HPLC content determination. 32 of the 40 batches of samples were in accordance with the Chinese Pharmacopoeia. 1 batch was derived from Changshanhu pomelo, a local customary variety. The other 7 batches were from orange. 40 lots of Fructus Aurantii samples. 16 batches were from Jiangxi province, 10 batches from Zhejiang province, 12 batches from Anhui province, and 1 lot from Hunan province, all of which were the main producing areas of Fructus Aurantii, and another batch was from Hubei province. Conclusion: the composition of Fructus Aurantii is affected by variety, origin and harvest time. At present, the varieties of Fructus Aurantii in the terminal market of Fructus Aurantii are confused and the quality is uneven. The supervision of the market of Fructus Aurantii needs to be strengthened in order to ensure the safety and effectiveness of drug use by consumers.
【作者单位】：衢州市食品药品检验所;衢州职业技术学院;
【基金】：浙江省食品药品监督管理局科技专项(No.2014006) 浙江省衢州市科技计划项目(No.2014J018;2014Y021) 衢州职业技术学院重点科研项目(No.QZYZ1406)
【分类号】：R95

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