妇产科医院门诊超药品说明书用药情况调查与分析

发布时间：2018-07-17 04:59

【摘要】：目的:为规范超说明书用药及保证临床合理用药提供参考。方法:通过等间隔方式抽取我院2016年1-3月门诊处方2 400张进行处方分析,按照药品说明书将超说明书用药分为超适应证用药、超剂量用药、超给药途径用药及超人群用药;通过查阅国内外药品说明书、国内外指南、国内外文献及MICROMEDEX Health Care Series数据库等对超说明书用药进行分析。结果:超说明书用药处方有219张(9.1%),共涉及药品12种、超说明书用药38项,主要表现为超适应证用药219张(100%),其中合并超人群用药4张(1.8%)。各项超说明书用药用法均有证据支持,其中9项(23.7%)超说明书用药用法已被MICROMEDEX收录。最常见超说明书用药的药品为戊酸雌二醇片(22.8%)、盐酸二甲双胍片(17.4%)和炔雌醇环丙孕酮片(12.3%)。结论:我院门诊超说明书用药均有证据支持,但各证据质量存在差异。临床确需超说明书用药时需充分权衡利弊,建立相应的临床应用管理制度与流程,尽量规避医疗风险,保障患者用药安全。
[Abstract]:Objective: to provide a reference for standardizing drug use and ensuring rational drug use in clinical practice. Methods: 2 400 prescriptions from outpatient clinic of our hospital from January to January 2016 were collected and analyzed by equal interval. According to the drug instructions, the drugs were divided into overindication, overdose, overdose and overdose. By consulting domestic and foreign drug instructions, domestic and foreign guidelines, domestic and foreign literature and MICROMEDEX Health Care Series database, the analysis of drug hyperinstructions was carried out. Results: there were 219 prescriptions (9.1%) for superprescriptions, involving 12 kinds of drugs, 38 of which were superprescriptions, including 219 (100%) of superindications, 4 (1.8%) of which were combined with superprescriptions. There was evidence to support the use of supermanual drugs, of which 9 items (23.7%) had been recorded by MICROMEDEX. Estradiol valerate tablets (22. 8%), metformin hydrochloride tablets (17. 4%) and cyproprogesterone tablets (12. 3%) were the most common drugs. Conclusion: there is evidence to support the use of drugs in our outpatient department, but the quality of evidence is different. In order to avoid the medical risk and ensure the safety of drug use, the clinical application management system and process should be established.
【作者单位】：复旦大学附属妇产科医院药剂科;
【分类号】：R95

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