两种方法测定马尔尼菲青霉酵母相体外药敏试验的一致性研究
发布时间:2018-10-26 17:56
【摘要】:正双相真菌马尔尼菲青霉(Penicillium marneffei,PM)感染所致的马尔尼菲青霉病(Penicilliosis marneffei,PSM)是导致我国南方,尤其是广西、广东地区艾滋病患者死亡的主要感染因素[1,2]。PM可致全身多器官侵袭感染,如得不到正确治疗病死率高。然而,目前对PSM抗真菌药物的选择仍主要依靠临床经验,缺乏体外药敏结果的支持,其重要原因与尚未建立标准的
[Abstract]:Penicillium marneffei (Penicilliosis marneffei,PSM) caused by the positive biphasic fungus Penicillium marneffei (Penicillium marneffei,PM) is a cause of penicilliosis marneffei in southern China, especially in Guangxi. The main infection factors of AIDS patients in Guangdong area. PM can cause multiple organ invasion and infection, if not treated correctly, the mortality rate is high. However, at present, the selection of antifungal drugs for PSM is still mainly based on clinical experience, which lacks the support of drug sensitivity results in vitro.
【作者单位】: 广西医科大学第一附属医院皮肤性病科、广西艾滋病防治研究重点实验室;
【基金】:广西卫生厅自筹课题(Z2007082,Z2014044) 国家自然科学基金(81060128,81271804) 广西自然科学基金(0991144,2012jj AA40175)资助项目
【分类号】:R927.2
[Abstract]:Penicillium marneffei (Penicilliosis marneffei,PSM) caused by the positive biphasic fungus Penicillium marneffei (Penicillium marneffei,PM) is a cause of penicilliosis marneffei in southern China, especially in Guangxi. The main infection factors of AIDS patients in Guangdong area. PM can cause multiple organ invasion and infection, if not treated correctly, the mortality rate is high. However, at present, the selection of antifungal drugs for PSM is still mainly based on clinical experience, which lacks the support of drug sensitivity results in vitro.
【作者单位】: 广西医科大学第一附属医院皮肤性病科、广西艾滋病防治研究重点实验室;
【基金】:广西卫生厅自筹课题(Z2007082,Z2014044) 国家自然科学基金(81060128,81271804) 广西自然科学基金(0991144,2012jj AA40175)资助项目
【分类号】:R927.2
【参考文献】
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1 曹存巍;万U,
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