非层状液晶系统在药剂学中的研究进展

发布时间：2018-11-13 09:03

【摘要】：目的对近年来非层状液晶在药剂学中的研究进展进行综述,为非层状液晶的进一步研究提供思路。方法溶致液晶相根据内部结构的不同可以分为层状液晶和非层状液晶,非层状液晶比层状液晶具有较高的稳定性和包封率等优势,因此该体系作为药物载体的研究引起了人们极大的兴趣。本文作者参阅国内外代表性文献,对其进行分析、归纳和整理后进行综述。结果对非层状液晶的制备材料、制备工艺及作为药物载体的现状进行了综述。结论非层状液晶在药物载体的应用中具有明显的优势。
[Abstract]:Objective to review the research progress of nonlamellar liquid crystals (NLCs) in pharmacy in recent years, and to provide some ideas for further research on NLCs. Methods the lyotropic liquid crystal phase can be divided into lamellar liquid crystal and non-lamellar liquid crystal according to the different internal structure. The non-lamellar liquid crystal has higher stability and encapsulation efficiency than the lamellar liquid crystal. Therefore, the study of the system as a drug carrier has aroused great interest. The author of this paper, referring to the domestic and foreign representative literature, analyzes, sums up and summarizes it. Results the preparation of non-lamellar liquid crystals, the preparation process and the current status as drug carriers were reviewed. Conclusion Non-lamellar liquid crystal has obvious advantages in the application of drug carrier.
【作者单位】：哈尔滨医科大学药学院;哈尔滨医科大学附属第二医院药学部;
【基金】：国家自然科学基金资助项目(81102401)
【分类号】：R94

【共引文献】