某院急诊注射用质子泵抑制剂的临床应用分析

发布时间：2018-12-14 23:33

【摘要】：目的:对某院急诊注射用质子泵抑制剂(PPIs)的使用情况进行分析,为临床合理用药提供参考。方法:采用回顾性调查研究的方法,检索某院HIS,获取2015年7月份使用过注射用PPIs的急诊患者处方,依据SAHP(美国医院药师协会)指南及药品说明书对其临床应用进行合理性分析。结果:在1 754份处方中,统计结果显示某院急诊使用PPIs注射剂的临床诊断不符合使用指征占比24.7%,用法用量不合理的处方占比7.5%,联合用药不合理占比为1.7%,老年患者使用潘妥洛克日剂量超40 mg一项为5.4%,具有统计学意义,其合理性有待进一步讨论研究。结论:某院急诊科使用注射用质子泵抑制剂存在不合理现象。为减轻患者经济负担及降低用药风险,临床医生应规范诊疗行为,做到诊断与用药相适应,杜绝无正当理由超适应证用药;可通过处方点评或信息系统引导用药等干预措施来改善目前的用药现状。
[Abstract]:Objective: to analyze the use of proton pump inhibitor (PPIs) for injection in a hospital. Methods: a retrospective study was conducted to retrieve the prescriptions of HIS, obtained from emergency patients who had used PPIs for injection in July 2015. According to SAHP (American Association of Hospital Pharmacists) guidelines and drug instructions, the rationality of its clinical application was analyzed. Results: among 1 754 prescriptions, the statistical results showed that the clinical diagnosis of emergency use of PPIs injection in a hospital did not conform to the usage indication ratio of 24.7, and the proportion of prescriptions with unreasonable usage was 7.5%. The irrational proportion of combined drug was 1.7%, and the dosage of Pandolock was over 40 mg per day in elderly patients, which had statistical significance, and its rationality needed to be further discussed. Conclusion: the use of proton pump inhibitors for injection in emergency department of a hospital is unreasonable. In order to reduce the economic burden of patients and reduce the risk of drug use, clinicians should standardize their diagnosis and treatment behavior, adapt the diagnosis to the medication, and put an end to the overuse of drugs without proper reasons. Intervention measures such as prescription review or information system can be used to improve the current situation of drug use.
【作者单位】：广东省人民医院药学部广东省医学科学院;
【分类号】：R975

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